分子靶向抗肿瘤药物十年历程启迪  

Molecular targeted anti-tumor drugs development in past decade

作　　者：丁健[1] 

机构地区：[1]中国科学院上海药物研究所,上海201203

出　　处：《世界临床药物》2012年第1期40-44,共5页World Clinical Drug

摘　　要：本文综合分析近十年来分子靶向抗肿瘤药物的历程,回顾各类分子靶向抗肿瘤药物的特点,提出分子靶向抗肿瘤药物开发中值得关注的几个问题:如药物的毒副作用、耐受性,个体化治疗与生物标志物,以及预测敏感患者生物标志物研究等。Several issues of molecular targeted anti-tumor drugs, such as drug adverse reactions, tolerance, individual therapy, as well as sensitive biomarkers are concerned. This review analyses the development in molecular targeted anti-tumor drugs in past decade.

关 键 词：分子靶向抗肿瘤药物 药物开发 个体化治疗 生物标志物 

分 类 号：R979.1[医药卫生—药品]