基于CT血管成像在体宫颈癌动脉血管网数字化三维模型的构建及意义  

The significance of the construction of digital three-dimensional model in vivo for arterial network of cervical cancer based on CTA

作　　者：陈春林[1] 段慧[1] 刘萍[1] 欧阳振波[1] 余艳红[1] 钟世镇[2] 许乙凯[3] 徐玉静[1] 郭传家[1] 毛东瑞[1] 王建平[3] 

机构地区：[1]南方医科大学南方医院妇产科,广东广州510515 [2]南方医科大学基础医学院解剖学教研室,广东广州510515 [3]南方医科大学南方医院影像中心,广东广州510515

出　　处：《中国实用妇科与产科杂志》2012年第1期23-26,共4页Chinese Journal of Practical Gynecology and Obstetrics

基　　金：国家自然科学基金(30970762);广东省自然科学基金(10151051501000102);(S2011010003830)

摘　　要：目的探讨利用CT血管成像(CTA)原始数据集构建在体宫颈癌动脉血管网数字化三维模型的方法及意义。方法 2010年5月在南方医科大学南方医院基于双源CTA技术,获取1例宫颈癌患者的CT-Dicom 3.0原始二维断层图像数据集。利用Mimics软件分别构建其骨盆、宫颈癌动脉血管网数字化三维模型并配准融合。结果构建的宫颈癌动脉血管网数字化三维模型不仅可以清楚地显示盆腔动脉血管网的各级分支,而且可多方位、多角度地观察各级动脉的管径、长度及分叉角度。此外,其还可进一步了解癌灶供血动脉及计算癌灶血容量。结论基于CTA数据集,应用计算机三维重建技术可构建出理想的宫颈癌动脉血管网数字化三维模型,为临床实现宫颈癌患者的个性化评估及治疗提供了平台。Objective To explore the method and significance for constructing the digital three-dimensional model in vivo for arterial network of cervical cancer based on computed tomographic angiography （CTA）. Methods A series of Dicom 3.0 images were obtained from a woman with cervical cancer by utilizing dual source CTA from Nanfang Hospital of Southern Medical UNiversity in May 2010. Then the Mimics 10.01 was used to construct the pelvic and the arterial network of cervical cancer. Results The digital model clearly showed the pelvic and arterial network, the model not only provided the 3D overview from mutil-direction and mutil-angles for doctors, but also could comprehend the arteries that supplyed the carcinoma and calculate the blood-volume. Conclusion Using related software like Mimics with database collected through CTA, the cervical cancer＇ s arterial network model in vivo could be successfully constructed, which may contribute to the materialization of digital models and be used for individualization evaluation and therapy.

关 键 词：CT血管成像 宫颈肿瘤 三维 数字化 动脉血管网 

分 类 号：R711[医药卫生—妇产科学]