Syntheses of N-sulfonyl-N,N-disubstituted amidines via a three-component free-radical coupling reaction of tertiary amines and arenesulfonyl azides with terminal alkynes  

作　　者：HE XinWei SHANG YongJia HU JinSong JU Kai JIANG Wei WANG SuFang 

机构地区：[1]Key Laboratory of Functional Molecular Solids,Ministry of Education,Anhui Key Laboratory of Molecule-Based Materials,College of Chemistry and Materials Science,Anhui Normal University,Wuhu 241000,China

出　　处：《Science China Chemistry》2012年第2期214-222,共9页中国科学(化学英文版)

基　　金：National Natural Science Foundation of China (20872001);the Anhui Education Department (TD200707 & KJ2008A064);the Program for the NCET (NCET-10-0004);the Research Culture Funds of Anhui Normal University (2010rcpy041) for their financial support

摘　　要：A facile and efficient synthesis of N-sulfonyl-N,N-disubstituted amidines has been achieved via a CuI-catalyzed three-component free-radical coupling reaction of tertiary amines and arenesulfonyl azides with terminal alkynes in the presence of azodiisobutyronitrile(AIBN).The reaction mechanism of this reaction has also been studied.A facile and efficient synthesis of N-sulfonyl-N,N-disubstituted amidines has been achieved via a CuI-catalyzed three-component free-radical coupling reaction of tertiary amines and arenesulfonyl azides with terminal alkynes in the presence of azo- diisobutyronitrile (AIBN). The reaction mechanism of this reaction has also been studied.

关 键 词：free radical multicomponent reaction sulfonyl azide terminal alkyne 

分 类 号：O621.3[理学—有机化学]