2010年我院617例药品不良反应报告分析  

ADR Cases Reported in Our Hospital:Analysis of 617 Cases in 2010

作　　者：朱虹云[1] 洪滟[1] 朱雅艳[1] 

机构地区：[1]浙江省丽水市中心医院,浙江丽水323000

出　　处：《中国药业》2012年第2期50-52,共3页China Pharmaceuticals

摘　　要：目的探讨医院药品不良反应(ADR)发生的特点及一般规律。方法对2010年收集到的617例药品不良反应报告,分别从患者性别、年龄、给药途径、用药情况、药品不良反应累及器官或系统及临床表现等方面进行统计、分析。结果引发药品不良反应最常见的药物为抗感染药物(267例)与中药制剂(70例)。所累及的器官或系统以皮肤及其附件损害最常见,有237例(38.41%);其次为消化系统损害125例(20.26%)。新的药品不良反应88例,严重的药品不良反应62例,其中新的、严重的药品不良反应8例。结论临床应重视药品不良反应监测工作,以减少或避免药品不良反应发生。Objective To investigate the characteristics and regularity of adverse drug reaction（ADR）occurred in our hospital.Methods 617 ADR cases reported in our hospital in 2010 were analyzed statistically in respect of patients＇sex and age,routes of administration,use of drugs,organs and systems involved in ADR and its clinical manifestations,etc.Results Of 617 ADR cases,267 cases and 70 cases were caused by anti-infectious agent and traditional Chinese medicine.The most common manifestation of ADR cases were injury of lesion of skin（237 cases）accounting for 38.41%,followed by digestive system and its appendants（125 cases）accounting for 20.0%.There were new ADR of 88cases,severe ADR of 62 cases and new severe ADR of 8 cases.Conclusion Great importance should be attached to ADR monitoring in order to reduce the incidence of ADR.

关 键 词：药品不良反应 报告分析 合理用药 

分 类 号：R954[医药卫生—药学] R969.3