小鼠耳蜗发育的形态学研究  

MORPHOLOGICAL STUDY ON THE DEVELOPMENT OF MOUSE COCHLEA

作　　者：赵玉林[1] 董明敏[1] 李晓萍[2] 董民声[1] 

机构地区：[1]河南医科大学第一附属医院耳鼻咽喉科,郑州450052 [2]河南医科大学第一附属医院药剂科,郑州450052

出　　处：《解剖学杂志》2000年第1期69-72,共4页Chinese Journal of Anatomy

摘　　要：目的：探讨小鼠耳蜗发育的特点及规律。方法：应用光镜对昆明种小白鼠耳蜗从胚胎第１０天至出生后第１４天的整个发育过程进行形态学研究。结果：小鼠耳蜗的整个形态发育过程可分为三个时期：（１）听泡发育期：（２）蜗管上皮增殖期 ；（３）耳蜗各部分结构的分化期和发育成熟期。结论：小鼠在出生时，其耳蜗膜迷路的大部分结构成份已经形成，出生后则需进一步的分化发育，至出生后２周时才完全发育成熟。小鼠耳蜗管上皮的分化是从底周经蜗管中部逐渐向顶周进行。To explore the character and rules of cochlea development in mice. Methods: The developing cochlea of Kunming strain white mice, ageed from tenth embryonic day (E10) to 14 day postnatal (P14), were studied by light microscopy. Results: The development process of cochlea may be divided into 3 periods according to the morphological changes, they are: (l)the development stage of otocyst ; (2) the proliferative stage of the epithelia of cochlear duct ; (3) the stage of differentiation and maturation of cochlear structures. Conclusion: The major components of the membranous labyrinth has formed when the mouse is born. Postnatal development takes the form of the structures it takes 2 weeks after birth to achieve full development. Differentiation of the epithelia begins in the hasal turn and extends apically as cochlear duct coils.

关 键 词：耳蜗 感觉上皮 发育 小鼠 形态学 

分 类 号：R322[医药卫生—人体解剖和组织胚胎学]