离子色谱法测定化妆品中的海藻糖  

Quick determination of trehalose in cosmetics by ion chromatography

作　　者：许丽[1] 周光明[1] 余娜[1] 张丽贤[1] 熊建飞[1] 

机构地区：[1]西南大学化学化工学院,重庆400715

出　　处：《日用化学工业》2012年第1期76-78,共3页China Surfactant Detergent & Cosmetics

基　　金：科技部重大专项资助项目(2008ZX07315);重庆市自然科学基金资助项目(CSTC2007BB5370)

摘　　要：建立了一种高效阴离子交换-脉冲安培检测(HPAE-PAD)测定化妆品中海藻糖的方法。采用不同的样品前处理方法,用METROSEP CARB 1分离柱(150 mm×4.0 mm)进行分离,以200.0 mmol·L-1的NaOH溶液为流动相进行洗脱,7 min内可完成对样品的分析。结果表明,海藻糖的检出限为0.02 mg·L-1,峰面积的相对标准偏差为0.17%,保留时间的相对标准偏差为0.28%;化妆品中常见的甘油和丙二醇不会对其测定产生干扰,平均回收率为95.2%～99.2%。An analysis method for determining trehalose in cosmetics based on high performance anion exchange chromatography with pulsed amperage detection （ HPAE - PAD） was established. Various sample pretreatment methods were adopted. The samples were analyzed by ion chromatography with METROSEP CARB 1 column （150 mm 4. 0 mm）. NaOH solution of 200. 0 mmol · L-1 was used asthe mobile phase for elution. Analysis of a sample can be completed within 7 min. The detection limit of trehalose was 0. 02 mg · L-l. The RSD of peak area achieves 0. 17%, and the RSD of retention time achieves 0. 28%. Glycerol and propylene glycol which can be easily found in cosmetics have no interference on the determination of the trehalose. The average recoveries achieves 95.2% - 99. 2%.

关 键 词：化妆品 海藻糖 离子色谱法 脉冲安培检测 

分 类 号：TQ658[化学工程—精细化工]