贵州省麻疹病例传播链及漏报调查分析  

Analysis and Investigation on Chain of Transmission of Measles Cases and Missing Report in Guizhou Province

作　　者：朱青[1] 吴升伟[1] 徐飞[1] 唐宁[1] 杜雯[1] 

机构地区：[1]贵州省疾病预防控制中心,贵阳550004

出　　处：《中国疫苗和免疫》2011年第6期523-525,共3页Chinese Journal of Vaccines and Immunization

基　　金：贵州省科学技术基金项目[编号(:2004)3066]

摘　　要：目的分析贵州省麻疹减毒活疫苗(Measles Attenuated Live Vaccine,MV)强化免疫活动(Supplementary Immunization Activities,SIA)后,麻疹病例的感染来源和麻疹监测系统(Measles Surveillance System,MSS)的敏感性,探讨在较大地理范围内开展高质量MVSIA能否实现一次性消除麻疹。方法采用随机抽样的方法进行横断面调查,综合分析麻疹病例感染、居民及医疗机构漏报资料。结果贵州省MVSIA后,麻疹病例中66.7%(24/36)无MV接种史,44.4%(16/34)为流动儿童,41.7%(15/34)的病例发病前有外出史。居民漏报率和医疗机构漏报率分别为12.9%(4/31)和6.3%(4/63)。结论在一个省开展MVSIA不能实现消除麻疹,为实现消除麻疹的目标,应考虑在全国范围内同步开展MVSIA,并应重点关注流动儿童的预防接种,加强常规免疫,提高MSS的敏感性,对每一例麻疹确诊病例周围进行及时调查和处置。Objective To analyze infection resource of measles cases and sensitivity of measles surveillance system （MSS） after measles attenuated llve vaccine （MV） supplementary immunization activity （SIA）in Guizhou province, and explore whether measles can be eliminated by high quality MV SIA in large scope. Methods Using cross-sectional study by random sampling, to analyze the infection resource of infected measles virus, missing report of resident and medical institutions. Results 66.7%（24/36）has no history of MV, 44.4%（16/34）is migrant children, and 41.7%（15/34）has the history of going out before onset measles. Missing report rate of resident and medical institutions is 12.9% （4/31 ）and 6.3% （4/63）respectively. Conclusion It is impossible to eliminate measles by MV SIA in one province. In order to elimination measles, it should be discussed to conduct MV SIA nationally at same time, and to pay more attention to migrant children, strengthen routine immunization, raise sensitivity of MSS, and conduct epidemiological survey timely to each measles case confirmed.

关 键 词：麻疹病例 传播链 漏报调查 

分 类 号：R511.1[医药卫生—内科学] R186[医药卫生—临床医学]