改良负压封闭引流技术治疗糖尿病足的疗效观察  

Clinical application of improved vacuum sealing drainage on diabetic foot ulcers

作　　者：邹晓防[1] 李斌[1] 宋卫平[1] 李健[1] 徐珊[1] 李晔琼[1] 谢晓繁[1] 危义乾[1] 曹卫红[1] 

机构地区：[1]空军总医院烧伤整形科,北京100142

出　　处：《感染．炎症．修复》2011年第4期238-240,F0003,共4页Infection Inflammation Repair

摘　　要：目的:观察应用改良负压封闭引流(VSD)技术治疗糖尿病足的效果。方法:将糖尿病足40例患者随机分为对照组和治疗组。对照组应用传统VSD技术治疗,治疗组应用改良VSD技术治疗,即在VSD敷料中增加一根冲洗管,经冲洗管每日1次注入呋喃西林500 ml和表皮生长因子30 ml,30 min后关闭冲洗管,开启负压。于治疗10 d后开启创面,比较两组创面愈合率、肉芽生长情况评分、堵管率以及患者住院时间和住院费用等。结果:治疗组创面愈合率[(35.3±4.4)%]和肉芽生长情况评分[(2.9土0.8)分]明显高于对照组[分别为(20.4±3.9)%和(2.1±0.5)分,P<0.05)],堵管率、住院费用和住院时间[0、(48.6±4.6)d,(8.7±1.8)万元]显著低于对照组[15.0%,(64.6±5.5)d,(10.0士2.1)万元,P<0.05]。结论:改良VSD技术较传统VSD技术更能促进糖尿病足肉芽组织生长,促进创面愈合,降低住院费用,缩短住院时间,是治疗糖尿病足的有效方法。Objective： To investigate the effect of improved vacuum sealing drainage （VSD） on the wound healing of open wounds of diabetic foot. Methods： Forty patients with diabetic foot ulcers wounds were divided randomly into control group and treatment group. Patients in control group were treated with routine VSD, while patients in treatment group were treated with improved VSD, in which irrigation with 500 ml of nitrofural and application of epithelial growth factor 30 ml for 30 minutes every day via an inserted suction pipe. The rate of wound healing, growth of granulation tissue, rate of suction pipe blockage 10 days after VSD treatment, as well as the time and expenses of patient in hospital was recorded. Results： There were no suction pipe blockage in treatment group but the rate was 15.0% in the control group （P〈0. 05）. The rate of wound healing [（35.3±4. 4）%] and score of granulation tissue growth （2.9±0. 8） in treatment group were higher than those in control group [-（20.4 ± 3.9）% and 2.1 ± 0. 5, P〈0. 05], while the time and expenses of patient in hospital [-（48. 6±4. 6）days, （8. 7±1.8） × 10^4 yuan] were significantly lower than those in control [（64.6±5.5）days, （10. 0±2. 1） ）〈 10^4 yuan, both P〈0. 05]. Conclusions： Improved VSD can effectively stimulate the growth of granulation tissue and healing of wounds, reduce the expenditure of patients. It is an ideal method to repair diabetic ulcers.

关 键 词：负压封闭引流 溃疡 糖尿病足 修复 

分 类 号：R473.6[医药卫生—护理学]