降钙素原在儿科感染性疾病诊断中的应用  

Procalcitonin in diagnosis of pediatric infectious diseases

作　　者：王耀华[1] 

机构地区：[1]湖北省黄石市中心医院儿科,湖北黄石435000

出　　处：《医药论坛杂志》2011年第23期73-74,77,共3页Journal of Medical Forum

摘　　要：目的探讨降钙素原在儿科感染性疾病诊断中应用的临床意义。方法采用血清半定量免疫色谱法测定120例患儿和40例健康儿童PCT水平,120例患儿分为局部感染组50例,重症感染组40例和病毒感染组30例,比较分析各组测定结果和阳性率,进行统计学分析。结果重症感染与局部感染组比较,差异有显著性(P<0.01);重症感染与病毒感染组比较,差异有显著性(P<0.01);重症感染与健康组比较,差异均有统计学意义(P<0.01)。结论 PCT有助于临床鉴别全身重症感染与局部轻症感染、病毒及结核感染与细菌感染、非感染性疾病与感染性疾病,其也可作为儿科败血症及严重感染时一个重要指标和诊断参数,指标与病情严重程度相关。Objective To investigate the clinical significance of the application of procalcitonin（PCT） in the diagnosis of pediatric infectious diseases.Methods Semi-quantitative serum immune chromatography 120 cases and 40 healthy children,children with PCT levels,120 patients were divided into groups of local infection in 50 cases,40 cases of severe infection and viral infection,30 patients,a comparative analysis of each group measurement results and the positive rate,for statistical analysis.Results Severe infection and local infection group,the difference was significant（P0.01）;severe infection and viral infection group,the difference was significant（P0.01）;severe infection with the healthy group,the differences were statistically significance（P0.01）.Conclusions PCT help clinicians to identify local mild infection and severe systemic infections,viral infections and bacterial infections and tuberculosis,non-infectious diseases and infectious diseases,which can be used as pediatric sepsis and severe infection,an important indicator and diagnostic parameters,index and disease severity.

关 键 词：降钙素原 儿科 感染性疾病 

分 类 号：R446.1[医药卫生—诊断学]