左旋氧氟沙星与氧氟沙星治疗尿路感染的疗效比较  

A COMPARISON OF THERAPEUTIC EFFECTS OF LEVOFLOXACIN AND OFLOXACIN IN THE TREATMENT OF URINARY TRACT INFECTIONS

作　　者：葛煜强[1] 吴兆龙[1] 陶凤武[1] 

机构地区：[1]上海医科大学附属中山医院肾内科,上海200032

出　　处：《中国新药杂志》2000年第1期48-49,共2页Chinese Journal of New Drugs

摘　　要：目的 :比较左旋氧氟沙星和氧氟沙星治疗尿路感染的疗效。方法 :　 5 0例尿路感染患者分成 2组 :左旋氧氟沙星治疗组 2 5例 ,0 .1～ 0 .2g ,bid ,po ;氧氟沙星治疗组 2 5例 ,0 .1～ 0 .2 g ,bid ,po。疗程为 5～ 14d。 结果 :左旋氧氟沙星和氧氟沙星治疗尿路感染的有效率分别为 92 %和 84 % ,痊愈率分别为 76%和 60 % ,均无显著性差异。但左旋氧氟沙星对复杂性慢性肾盂肾炎的疗效显著高于氧氟沙星。结论 :左旋氧氟沙星在治疗尿路感染中较氧氟沙星更为有效。OBJECTIVE:To compare the efficacy between levofloxacin and ofloxacin in the treatment of uninary infection.METHODS:50 patients with urinary infection were equally divided into two groups.Each group was treated with levofloxacin or ofloxacin in a regimen of 0.1～0.2g,bid for 5～14 days for both.RESULTS:There were no significant difference in effective rate and cure rate of levofolxacin and ofloxacin( P >0.05)but Levofloxacin is superior to ofloxacin in treatment of complicated chronic pyelonephritis.CONCLUSION:Levofloxacin may be more effective in the treatment of urinary tract infection than ofloxacin.

关 键 词：左旋氧氟沙星 氧氟沙星 尿路感染 治疗 

分 类 号：R691.305[医药卫生—泌尿科学]