补锌对骨折区和非骨折区骨锌含量影响的比较研究  

A comparative study of effects of zinc on bone zinc content in fractured-area and unfractured-area

作　　者：杨莽[1] 姚隆浩[2] 王国民[2] 徐兵[2] 陈阳[2] 杨文君[2] 

机构地区：[1]上海市东方医院口腔科,200120 [2]上海第二医科大学口腔医学院

出　　处：《现代口腔医学杂志》2000年第1期30-31,共2页Journal of Modern Stomatology

摘　　要：目的　本研究主要分析损伤后外源性锌剂在不同类型骨中的沉积规律。方法　选用 2 4只新西兰兔 ,首先形成双侧颧骨骨折模型。术后 1、2、3、4周分别测定骨折区 (颧骨 )和非骨折区 (下颌骨和颅骨 )骨锌的含量。结果　外源性锌剂在骨折区和非骨折区的沈积量均明显增加 ,但增加的时相不同 ;骨折区第 2周对锌的需要量最大 ,非骨折区第 2周骨锌含量明显下降。结论　外源性锌剂进入机体后主要贮存在骨髂系统 ,骨折愈合需要锌的参与 ,骨折后Objective The purpose of this study was to investigate the effects of zinc on bone zinc content in fractured-area during fracture healing.Methods 24 New Zealand Rabbits with bilateral zygomatic fractures were studied.The animals were sacrificed 1、2、3、4 weeks postoperatively and bone zinc content in fractuerd-area and unfuactured-area were investigated.Results Bone zinc content increased in both fractured and unfractured bone,and it reached to the top livel at second week in fractured-area while markedly decreased at the same time in unfractured-area.Conclusion Zinc deposit mainly in bone system.Extra zinc supplement in early two weeks can improve the fracture healing.

关 键 词：骨折愈合 骨 锌含量 比较研究 

分 类 号：R683.4[医药卫生—骨科学]