尿C肽肌酐比值是门诊鉴别HNF1α/HNF4αMODY与长病程1型糖尿病的实用诊断工具  

Urinary C-peptide creatinine ratio(UCPCR) is a practical outpatient tool for identifying HNF1A/HNF4A MODY from long duration type 1 diabetes

作　　者：洪珊珊(摘译)[1] 钱荣立(审校)[1] 

机构地区：[1]《中国糖尿病杂志》编辑部,北京100034

出　　处：《中国糖尿病杂志》2012年第1期79-80,共2页Chinese Journal of Diabetes

摘　　要：Besser REJ,Knight BA,Shepherd MH等的"Urinary C-peptide creatinine ratio(UCPCR)is a practical outpatient tool for identifying HNF1A/HNF4A MODY from long duration type 1diabetes"(Diabetes Care,2011,34:286-291)一文比较了成人中HNF1A/4A MODY、T1DM、T2DM中的UCPCR水平,证实了UCPCR是可用于鉴别HNF1α/HNF4αMODY与长期T1DM的非侵入性门诊诊断工具。并指出对于从病程>5年的T1DM和MODY的鉴别,UCPCR可用于确定是否需要基因检测。Besser REJ,Knight BA,Shepherd MH,et al compared stimulated UCPCR in adults with HNF1A/4A MODY,type 1diabetes,and type 2diabetes in＂Urinary C-peptide creatinine ratio（UCPCR）is a practical outpatient tool for identifying HNF1A/HNF4A MODY from long duration type 1 diabetes＂（Diabetes Care,2011,34：286-291）,and concluded UCPCR was a noninvasive outpatient tool that can be used to discriminate HNF1A and HNF4A MODY from long-duration type 1 diabetes.To differentiate MODY from type 1diabetes of〉5years’duration,UCPCR could be used to determine whether genetic testing is indicated.The essential parts were tanslated in the following article.

关 键 词：糖尿病 1型 HNF1A/HNF4AMODY 尿C肽肌酐比值 

分 类 号：R587.1[医药卫生—内分泌]