Peptide friction in water nanofilm on mica surface  

作　　者：Zhou Bo Xiu Peng Wang Chun-Lei Fang Hai-Ping 周波;修鹏;王春雷;方海平(Department of Physical Biology and Department of Microscopic Water Dynamics,Shanghai Institute of Applied Physics,Chinese Academy of Sciences,P.O.Box 800-204,Shanghai 201800,China;Graduate School of the Chinese Academy of Sciences,Beijing 100190,China;Bio-X Laboratory,Department of Physics,Zhejiang University,Hangzhou 310027,China;Theoretical Physics Center for Science Facilities,Chinese Academy of Sciences,19(B)Yuquan Road,Beijing 100049,China)

机构地区：[1]Department of Physical Biology and Department of Microscopic Water Dynamics,Shanghai Institute of Applied Physics,Chinese Academy of Sciences,P.O.Box 800-204,Shanghai 201800,China [2]Graduate School of the Chinese Academy of Sciences,Beijing 100190,China [3]Bio-X Laboratory,Department of Physics,Zhejiang University,Hangzhou 310027,China [4]Theoretical Physics Center for Science Facilities,Chinese Academy of Sciences,19(B)Yuquan Road,Beijing 100049,China

出　　处：《Chinese Physics B》2012年第2期431-436,共6页中国物理B（英文版）

基　　金：supported by the National Natural Science Foundation of China (Grant No.10825520);the National Basic Research Program of China (Grant No.2007CB936000);the National Science Foundation for Post-Doctoral Scientists of China (Grant No.20100480645)

摘　　要：Peptide frictions in water nanofilms of various thicknesses on a mica surface are studied via molecular dynamics simulations. We find that the forced lateral motion of the peptide exhibits stick-slip behaviour at low water coverage; in contrast, the smooth gliding motion is observed at higher water coverage. The adsorbed peptide can form direct peptide-surface hydrogen bonds as well as indirect peptide-water-surface hydrogen bonds with the substrate. We propose that the stick-slip phenomenon is attributed to the overall effects of direct and indirect hydrogen bonds formed between the surface and the peptide.Peptide frictions in water nanofilms of various thicknesses on a mica surface are studied via molecular dynamics simulations. We find that the forced lateral motion of the peptide exhibits stick-slip behaviour at low water coverage; in contrast, the smooth gliding motion is observed at higher water coverage. The adsorbed peptide can form direct peptide-surface hydrogen bonds as well as indirect peptide-water-surface hydrogen bonds with the substrate. We propose that the stick-slip phenomenon is attributed to the overall effects of direct and indirect hydrogen bonds formed between the surface and the peptide.

关 键 词：peptide friction water nanofilm mica surface molecular dynamics simulation 

分 类 号：O484.2[理学—固体物理]