Characteristics analysis of acupuncture electroencephalograph based on mutual information Lempel-Ziv complexity  

作　　者：Luo Xi-Liu Wang Jiang Han Chun-Xiao Deng Bin Wei Xi-Le Bian Hong-Rui 罗昔柳;王江;韩春晓;邓斌;魏熙乐;边洪瑞(School of Electrical and Automation Engineering,Tianjin University,Tianjin 300072,China;School of Automation and Electrical Engineering,Tianjin University of Technology and Education,Tianjin 300222,China)

机构地区：[1]School of Electrical and Automation Engineering,Tianjin University,Tianjin 300072,China [2]School of Automation and Electrical Engineering,Tianjin University of Technology and Education,Tianjin 300222,China

出　　处：《Chinese Physics B》2012年第2期561-568,共8页中国物理B（英文版）

基　　金：supported by the Key Program of the National Natural Science Foundation of China (Grant No.50537030);the National Natural Science Foundation of China (Grant No.61072012);the Young Scientists Fund of the National Natural Science Foundation of China (Grant Nos.50907044,61104032,and 60901035)

摘　　要：As a convenient approach to the characterization of cerebral cortex electrical information, electroencephalograph （EEG） has potential clinical application in monitoring the acupuncture effects. In this paper, a method composed of the mutual information method and Lempel-Ziv complexity method （MILZC） is proposed to investigate the effects of acupuncture on the complexity of information exchanges between different brain regions based on EEGs. In the experiments, eight subjects are manually acupunctured at ＇Zusanli＇ acupuncture point （ST-36） with different frequencies （i.e., 50, 100, 150, and 200 times/min） and the EEGs are recorded simultaneously. First, MILZC values are compared in general. Then average brain connections are used to quantify the effectiveness of acupuncture under the above four frequencies. Finally, significance index P values are used to study the spatiality of the acupuncture effect on the brain. Three main findings are obtained： （i） MILZC values increase during the acupuncture; （ii） manual acupunctures （MAs） with 100 times/rain and 150 times/min are more effective than with 50 times/min and 200 times/rain; （iii） contralateral hemisphere activation is more prominent than ipsilateral hemisphere＇s. All these findings suggest that acupuncture contributes to the increase of brain information exchange complexity and the MILZC method can successfully describe these changes.As a convenient approach to the characterization of cerebral cortex electrical information, electroencephalograph （EEG） has potential clinical application in monitoring the acupuncture effects. In this paper, a method composed of the mutual information method and Lempel-Ziv complexity method （MILZC） is proposed to investigate the effects of acupuncture on the complexity of information exchanges between different brain regions based on EEGs. In the experiments, eight subjects are manually acupunctured at ＇Zusanli＇ acupuncture point （ST-36） with different frequencies （i.e., 50, 100, 150, and 200 times/min） and the EEGs are recorded simultaneously. First, MILZC values are compared in general. Then average brain connections are used to quantify the effectiveness of acupuncture under the above four frequencies. Finally, significance index P values are used to study the spatiality of the acupuncture effect on the brain. Three main findings are obtained： （i） MILZC values increase during the acupuncture; （ii） manual acupunctures （MAs） with 100 times/rain and 150 times/min are more effective than with 50 times/min and 200 times/rain; （iii） contralateral hemisphere activation is more prominent than ipsilateral hemisphere＇s. All these findings suggest that acupuncture contributes to the increase of brain information exchange complexity and the MILZC method can successfully describe these changes.

关 键 词：ELECTROENCEPHALOGRAPH ACUPUNCTURE mutual information Lempel Ziv complexitymethod 

分 类 号：TN911.7[电子电信—通信与信息系统]