Purple membrane resists cell adhesion  

作　　者：ZHAO YingChun DING JianDong 

机构地区：[1]State Key Laboratory of Molecular Engineering of Polymers,Department of Macromolecular Science,Laboratory of Advanced Materials,FudanUniversity,Shanghai 200433,China

出　　处：《Chinese Science Bulletin》2012年第2期234-237,共4页

基　　金：supported by the National Basic Research Program of China (2009CB930000, 2011CB606203);the National Natural Science Foundation of China (21034002)

摘　　要：Bacteriorhodopsin is a well-known photoresponsive protein in the cell membrane of Halobacterium salinarum and exists in the patch called the purple membrane(PM).This letter reports,for the first time,its new function as a natural non-fouling substance for resisting cell adhesion.Mammalian cells such as murine preosteocytes MC3T3-E1 were seeded on the PM film.A significant resistance to cell adhesion on the film was found.Bacteriorhodopsin is a well-known photoresponsive protein in the cell membrane of Halobacterium salinarum and exists in the patch called the purple membrane （PM）. This letter reports, for the first time, its new function as a natural non-fouling substance for resisting cell adhesion. Mammalian cells such as murine preosteocytes MC3T3-E1 were seeded on the PM film. A significant resistance to cell adhesion on the film was found.

关 键 词：细胞粘附 紫膜 细菌视紫红质 光敏蛋白 哺乳动物 细胞膜 细胞株 附着力 

分 类 号：Q26[生物学—细胞生物学] Q734