自拟清化消瘀方辅治糖尿病患者颈动脉斑块临床观察  

Clinical observation of the self-developed Qinghuaxiaoyu decoction applied to treatment the patients with diabetic merging carotid artery plaque

作　　者：邓鸣[1] 张炜宁[1] 杨以超[1] 

机构地区：[1]湖南中医药大学附属深圳市福田中医院,518034

出　　处：《疑难病杂志》2012年第2期105-107,共3页Chinese Journal of Difficult and Complicated Cases

基　　金：深圳市科技计划项目(No.200903215)

摘　　要：目的观察自拟清化消瘀方辅治糖尿病颈动脉斑块的疗效。方法 60例糖尿病合并颈动脉斑块患者随机分为治疗组30例(清化消瘀方加西药常规治疗)、对照组30例(西药常规治疗),疗程4周,治疗前后监测糖化血红蛋白(HbA_(1c))、空腹血糖(FPG)、餐后2 h血糖(2 hPG)、血脂指标(TC、TG、LDL-C)及颈动脉内膜—中层厚度(IMT)等指标。结果 2组治疗后HbA_(1c)、FPG、2 hPG、TC、TG、LDL-C、IMT等指标均较治疗前显著改善,差异有统计学意义(P<0.05),且治疗后治疗组与对照组比较差异亦有统计学意义(P<0.05)。治疗组总有效率(86.7%)显著高于对照组(50.0%),差异有统计学意义(P<0.05)。结论自拟清化消瘀方联合西药能有效改善糖尿病患者血糖及血脂水平,抑制斑块的形成和发展,其疗效明显优于单用西药。Objective To observe the therapeutic effects of self-developed Qinghuaxiaoyu decoction on assistant treatment the carotid artery plaque with diabetic.Methods Consecutive 60 cases of patients with diabetes were divided into 2 groups randomly,one group was control group(n=30,treated with metformin hydrochioride tablets),the other was treatment group(n=30,treated with metformin hydrochioride tablets and Qinghuaxiaoyu decoction).The treatment course was 4 weeks.The HbA_(1c)、,FPG,2hPG,TC,TG,LDL-C and IMT were determined before and after the treatment.Results After treatment these indicators such as HbA_(1c),FPG,2hPG,TC,TG,LDL-C and IMT in both two group were obviously improved than those of before the treatment,the difference has statistic significance(P<0.05).Furthermore,the difference of comparing the indicators of the two groups after the treatment had statistic significance(P<0.05).The general effectiveness ratio of the treatment group(86.7%) was obviously better than that of in the control group(50.0%),and the difference had statistic significance.Conclusion The self-developed Qinghuaxiaoyu decoction was applied in assistant treatment western medicine could effectively lower the level of blood glucose,the blood lipid and suppress the forming and development of the plaque, in which way the treatment effect was obviously better than the way of using the western medicine only.

关 键 词：自拟清化消瘀方 糖尿病 颈动脉斑块 中医药疗法 

分 类 号：R259[医药卫生—中西医结合]