中药炉甘石的成分分析  

Analysis on constituents of traditional Chinese medicine galamina

作　　者：杨连菊[1] 张志杰[1] 李娆娆[1] 冯学锋[1] 杨京玉[1] 

机构地区：[1]中国中医科学院中药研究所,北京100700

出　　处：《中国中药杂志》2012年第3期331-334,共4页China Journal of Chinese Materia Medica

基　　金：国家"十一五"科技支撑计划项目(2008BAI55B02)

摘　　要：目的:对中药炉甘石进行全面成分分析,为炉甘石的质量控制提供依据。方法:采用偏光显微镜与电子探针对炉甘石的显微形貌和微区成分进行了定性、定量分析;采用等离子质谱法对炉甘石中42种元素进行了测定;采用药典法对炉甘石样品的主成分-氧化锌含量进行了测定。结果:炉甘石样品微区分析显示炉甘石质地疏松,由多种矿物颗粒散在共生,其主要矿物组成为水锌矿,其他尚可见菱锌矿、氧化锌、白云石、方解石等;市售炉甘石伪品泛滥;天然炉甘石样品中铅含量较高。结论:来源于天然矿物的炉甘石是多种矿物的共生集合体;市售炉甘石质量问题较多,应建立炉甘石药材的快速鉴别方法,炉甘石中有害元素控制限量标准,就解决炉甘石药材中有害元素超标的问题进行更深入的研究。Objective： To analyze constituents of traditional Chinese medicine galamina, and provide basis for the quality con- trol of galamina. Method： Polarization microscope and electron probe were adopted for a qualitative and quantitative analysis on microscopic appearance and micro-area constituents of galamina. Fourty-two elements contained in galamina were determined by the plasma mass-spectrometric method. Zinc oxide, the major constituent of galamina samples, was detected using the pharmacopeia method. Re- suit： The micro-area analysis on galamina samples showed that galamina is mainly constituted by various mineral particulates such as hydrozincite, smithsonite, zinc oxide and dolomite in a loose texture. It is also found that there are many counterfeit galamina sold in the market, marked by a high lead content in natural galamina samples. Conclusion： Galamina is a mineral aggregation of multiple natural mineral substances, but those sold in the market has many quality problems. Therefore, a fast method shall be established to identify the authenticity of galamina and a standard shall be set to control harmful elements contained in galamina. It is suggested to conduct in-depth studies on excessive harmful elements contained in galamina medicinal materials.

关 键 词：炉甘石 成分分析 矿物集合体 有害元素 

分 类 号：R284.1[医药卫生—中药学]