杂多酸及其盐催化D-果糖选择性合成5-羟甲基糠醛  

Selective Synthesis of HMF from D-Fructose Catalyzed by Heteropoly Acid and Its Salts

作　　者：刘欣颖[1] 邱俊杰[1] 周宇涵[1] 曲丽红[1] 曲景平[1] 

机构地区：[1]大连理工大学制药科学与技术学院精细化工国家重点实验室,辽宁大连116024

出　　处：《精细化工》2012年第2期130-133,204,共5页Fine Chemicals

基　　金：国家自然科学基金(20806012);辽宁省教育厅科学技术研究项目(2008S048)~~

摘　　要：考察了杂多酸及其盐对果糖脱水制备HMF的催化性能。研究表明,磷钨酸铯盐催化效果较好,高温反应对5-羟甲基糠醛(HMF)生成有利,添加助剂聚乙烯吡咯烷酮(PVP)可提高产率。通过对反应温度、催化剂、加料方式的考察,得出优化的反应条件为:将果糖溶于DMSO中,添加质量分数20%的PVP,升温至155℃加入占果糖摩尔分数1%的CsH2PW12O40,反应5 min,产率77.9%。The derivatives of 5-hydroxymethylfurfural are important materials for the synthesis of biodegradable polymers. It can be obtained by the dehydration of D-fructose in the presence of acid catalyst. The activity of heteropoly acid and its salts was investigated. In addition, the effect of the temperature, addition of PVP, and the charging method was studied. The results show that an elevated temperature favored high yields and the Cs salt of phosphotungstic acid ,especially CsH2PW12O40, gave good results. A optimum yield of 77.9% of HMF was obtained while using 1% （molar fraction） CsH2PW12O40 as catalyst,20% （mass fraction） PVP as additive,with the reaction taking place at 155℃ for 5 min.

关 键 词：生物质 果糖 5-羟甲基糠醛 杂多酸 杂多酸盐 催化技术 

分 类 号：TQ032.4[化学工程]