双核碱性功能化离子液体催化Knoevenagel缩合反应  

Knoevenagel condensation reaction catalyzed by functionalized basic bicationionic liquid

作　　者：徐玥[1] 梁金花[2] 任晓乾[1] 姜岷[2] 李振江[2] 

机构地区：[1]南京工业大学化学化工学院,江苏南京210009 [2]南京工业大学生物与制药工程学院,江苏南京210009

出　　处：《南京工业大学学报（自然科学版）》2012年第1期105-108,共4页Journal of Nanjing Tech University(Natural Science Edition)

基　　金：国家高技术研究发展计划(863计划)(2007AA06A402);国家重点基础研究发展计划(973计划)资助项目(2009CB724701)

摘　　要：采用咪唑与二溴烷烃为原料,两步法合成了5种新型咪唑类碱性双核功能化离子液体催化剂,考察了在醛与氰基化合物的Knoevenagel缩合反应中的催化性能。结果表明:咪唑类碱性双核功能化离子液体在Knoevenagel反应中具有很好的催化性能,在其中以双-(3-甲基-1-咪唑)亚丁基双氢氧化物离子液体的催化糠醛与丙二氰Knoevenagel缩合反应的活性最好,其产物的收率高达93.2%,而双-(3-甲基-1-咪唑)亚己基双氢氧化物离子液体对研究中的类醛与氰基化合物的Knoevenagel缩合反应都有较好的催化效果。The five basic bisnuclear functional ionic liquids with an imidazolium structure were synthesized by imidazole and dibromo alkanes.They were used as catalysts for the aldehyde and cyano compounds in the knoevenagel condensation reaction,and the catalytic properties were investigated.The results indicated that the basic bisnuclear functional ionic liquids had good catalytic performances in the Knoevenagel condensation.The condensation reaction reactivity between catalytic furfural of ion liquid bis-（3-methyl-l-imidazolium-） -butylene dihydroxide and Knoevenagel was the best one,and its yield of product was 93.2%.In general bis-（3-methyl-l-imidazolium-）-hexylidene dihydroxide performed the better catalytic effect in the four groups of aldehydes and cyano compounds in Knoevenagel condensation.

关 键 词：功能化离子液体 双核阳离子 碱催化 KNOEVENAGEL缩合反应 

分 类 号：TQ517.4[化学工程]