蛇毒血凝酶与蒙脱石散联合鼻饲治疗新生儿应激性溃疡出血疗效观察  

The Venom Blood Clots Enzyme and Montmorillonite Joint BiSi Treatment Scattered Newborn Stress Ulcer Bleeding Curative Effects

作　　者：丘冰青 张海燕 潘遂壮 杨鸣 吴军峰 

机构地区：[1]广东省连州市人民医院儿科,广东连州513404

出　　处：《中国医药指南》2012年第3期25-26,共2页Guide of China Medicine

摘　　要：目的探讨蛇毒血凝酶与蒙脱石散联合鼻饲治疗新生儿应激性溃疡出血的疗效。方法将我院2007年5月至2011年4月收治107例应激性溃疡出血新生儿随机分成治疗组58例和对照组49例。2组基础治疗相同,治疗组在此基础上加用蛇毒血凝酶与蒙脱石散联合鼻饲治疗,每日3次。治疗后观察临床疗效、出血停止时间,同时观察不良反应。结果治疗组总有效率为94.8%,止血时间为(1.01±0.487)d;对照组总有效率为79.6%,止血时间为(1.55±0.649)d。两组比较差异均有统计学意义(χ2=5.7765,P<0.05;t=4.924,P<0.05),且无不良反应发生。结论蛇毒血凝酶与蒙脱石散联用治疗新生儿应激性溃疡出血效果显著。Objective Study the venom blood clots enzyme and montmorillonite joint BiSi treatment scattered newborn stress ulcers the curative effect of bleeding.Methods from May 2007 to April 2011 in 107 cases of stress were bleeding ulcer neonatal randomly divided into treatment group and control group in 58 cases in 49 cases.Two the same basic therapy group,the treatment group based on this add with venom blood clots enzyme and montmorillonite joint BiSi scattered treatment,3 times a day.After treatment,the clinical curative effect of observation,bleeding stop time,and observed adverse reactions.Results the treatment group total effectiveness 94.8%,stop bleeding time for（1.01±0.487）d;The total effective rate of 79.6% in the control group,stop bleeding time for（1.55±0.649） d.Two groups of comparative differences are statistically significant（χ2=5.7765,P0.05;t= 4.924,P0.05）,and with no adverse reaction.Conclusion The venom blood clots enzyme and montmorillonite scattered coupled neonatal stress bleeding ulcer treatment effect is remarkable.

关 键 词：应激性溃疡 蛇毒血凝酶 蒙脱石散 

分 类 号：R722[医药卫生—儿科]