核苷类抗病毒药物阻断乙肝病毒母婴传播的研究进展  

Recent advances in research of nucleotide in preventing mother-to-infant transmission of hepatitis B virus

作　　者：朱科伦[1] 朱郇悯[2] 曾文铤[1] 梁建新[1] 

机构地区：[1]广州医学院第一临床学院传染病学与流行病学教研室,广州510120 [2]广州医学院,510182

出　　处：《广州医药》2012年第1期1-2,共2页Guangzhou Medical Journal

摘　　要：核苷类抗病毒药物能降低孕妇血中乙肝病毒载量,核苷类抗病毒药物联合新生儿接种乙肝免疫球蛋白(HBIG)、乙肝疫苗,阻断乙肝病毒母婴传播效果比新生儿单纯接种HBIG、乙肝疫苗的效果更好。孕妇和胎儿安全性等问题尚需深入研究。慢性乙型肝炎和携带病毒的孕妇可以考虑服用核苷类抗病毒药物,提高阻断乙肝病毒母婴传播的效果。HBV viral loads may be reduced by the nucleotide,nucleotide combining with HBIG and hepatitis B vaccine,was used in preventing mother-to-infant transmission of hepatitis B virus.It produced a effective result,the result was better than the effect of alone use of HBIG and hepatitis B vaccine on the newborn Infant.The safety of the pregnant women and the fetus should be studied.Nucleotide may be considered for preventing mother-to-infant transmission of hepatitis B virus.

关 键 词：核苷类抗病毒药 乙肝病毒 母婴传播 

分 类 号：R512.62[医药卫生—内科学]