液体药物预填充注射系统的发展现状  

Present Development Situation of Liquid Drug Prefilled Syringe System

作　　者：刘丽丽[1,2] 王成港[2] 龚莉[2] 王平保[2] 

机构地区：[1]天津医科大学,天津300070 [2]天津药物研究院药物制剂及释药技术国家重点实验室,天津300193

出　　处：《中国医药工业杂志》2012年第2期143-147,共5页Chinese Journal of Pharmaceuticals

基　　金：973计划课题(2010CB735602)

摘　　要：液体药物预填充注射系统因其安全有效而发展迅速。提高药物与注射器具间的相容性和保证使用安全性是本系统发展的关键问题。在制备不同性质药物的预填充给药系统时,应考虑预填充注射器各部件及其生产工艺的优缺点和适用范围。本文依据近年来国内外文献,分析并总结了液体药物预填充注射系统的发展及使用现状。Liquid drug prefilled syringe system develops quickly for its safety and efficacy. The key point of this system is to improve the compatibility of drug and injection device and ensure the safety use. The advantage, disadvantage and applicability of the components of prefilled syringe and manufacturing process should be taken into account in the preparation of prefilled syringe system loaded with different drugs. Based on the domestic and foreign literatures in recent years, the development and application of liquid drug prefilled syringe system are analyzed and summarized in this paper.

关 键 词：液体药物预填充注射系统 安全性 相容性 综述 

分 类 号：R944.11[医药卫生—药剂学]