Numerical simulation and experiment of optothermal response of biological tissue irradiated by continuous xenon lamp  

作　　者：黄梅珍 童雅星 

机构地区：[1]Institute of Optical Engineering, Department of Physics, Shanghai Jiao Tong University

出　　处：《Chinese Optics Letters》2012年第1期50-53,共4页中国光学快报（英文版）

基　　金：supported by the National Natural Science Foundation of China (No.60678054);the Key Laboratory of Optoelectronic Science and Technology for Medicine (Fujian Normal University),Ministry of Education,China

摘　　要：A finite element method computation model for analyzing optothermal interaction of polychromatic light and biology tissue is proposed and proven by experiment. A continuous xenon lamp is employed as an example. First, the spectral energy distribution of the xenon lamp is measured and found to be equivalent to a series of quasi-chromatic light with different central wavelengths, different energies, and certain bandwidth. Next, according to the reported thermal and optical parameters of porcine skin and porcine liver, the temporal temperature distributions of these tissues irradiated by each quasi-chromatic light are simulated. Then, the thermal effect is superimposed to obtain the whole optothermal temporal temperature distribution. Moreover, the optothermal response experiments of fresh porcine skin and porcine liver tissues irradiated by continuous xenon lamp are carried out. The results of the simulation and experiment are analyzed and compared, and are found to be commendably matched.A finite element method computation model for analyzing optothermal interaction of polychromatic light and biology tissue is proposed and proven by experiment. A continuous xenon lamp is employed as an example. First, the spectral energy distribution of the xenon lamp is measured and found to be equivalent to a series of quasi-chromatic light with different central wavelengths, different energies, and certain bandwidth. Next, according to the reported thermal and optical parameters of porcine skin and porcine liver, the temporal temperature distributions of these tissues irradiated by each quasi-chromatic light are simulated. Then, the thermal effect is superimposed to obtain the whole optothermal temporal temperature distribution. Moreover, the optothermal response experiments of fresh porcine skin and porcine liver tissues irradiated by continuous xenon lamp are carried out. The results of the simulation and experiment are analyzed and compared, and are found to be commendably matched.

关 键 词：EXPERIMENTS Finite element method HISTOLOGY Temperature distribution TISSUE 

分 类 号：Q63[生物学—生物物理学]