妥洛特罗经皮给药在婴幼儿病毒相关性喘息中的应用  

With lot of compass transdermal drug delivery in infantile virus--associated wheezing application

作　　者：庞戈红[1] 麦朝清[1] 

机构地区：[1]广东省珠海市妇幼保健院,珠海519000

出　　处：《按摩与康复医学》2012年第2期23-24,共2页Chinese Manipulation and Rehabilitation Medicine

摘　　要：目的 观察妥洛特罗经皮给药在婴幼儿病毒相关性喘息中的有效性及安全性.方法：将92例患儿随机分为治疗组（45例）及对照组（47例）.两组均给予相同的综合治疗（抗病毒、抗炎、祛痰、止咳等）以及布地奈德雾化液雾化吸入,治疗组加予妥洛特罗贴剂（0.5mg/贴）,睡前贴前胸;对照组联合硫酸特布他林雾化吸入.比较两组咳嗽缓解、喘息消失时间、住院时间及不良反应.结果：治疗组对照组主要症状、体征消失时间及住院时间比较,差异无统计学意义（P〉0.05）,治疗组副反应少.结论：治疗组妥洛特罗经皮给药治疗婴幼儿病毒相关性喘息疗效确切,具有起效快,副作用小,依从性好等优点.Objective：To observe the clinical effieney and safty of the tulobuterol patches in treating infants with asthmatic diseases relativity of vi- rus. Methods： 92 cases of infants were randomly divided into the controlgroup（45cases）and treatment group（47cases）, both groups were given the same comprehensive treatments（anti -- virus, anti- inflammatory, cough relieviry, phlegm dissipation, etc. ）, combine with facilitate expectoration budesonide solution inhalation, At the same time the treatment group use tulobuterol patches 0. 5rag by bedtime, while the control group add terbutal- ine sulphate aerosol solution inhalation. Compare the disappeared time of cough and wheezing, the average length of stay in hospital and the incidence of adverse reactions between two groups. Results：The treatment group and control group have no significant differences in treatment effct, but the tu- lobuterol patches group has fewer adverse reactions than terbutaline sulphate aerosol group. Conclusion：The tulobuterol patch in treating infants with asthmatic diseases has significant clinical effects with fewer side effects.

关 键 词：婴幼儿喘息 病毒 妥洛特罗贴剂 

分 类 号：R4[医药卫生—临床医学]