皮炎湿疹599例致病因素分析  

Pathogenesis Analysis of 599 Eczema Patients

作　　者：刘广仁[1] 韩永智[1] 黄庚史[1] 李邻峰[2] 

机构地区：[1]广东省人民医院、广东省医学科学院,广东广州510080 [2]北京大学第三医院,北京100191

出　　处：《中国皮肤性病学杂志》2012年第2期126-128,134,共4页The Chinese Journal of Dermatovenereology

摘　　要：目的探讨环境接触性因素在皮炎湿疹类疾病发病中的作用及影响因素。方法对诊断皮炎湿疹的患者做斑贴试验并进行问卷调查。结果 599例皮炎湿疹患者中变应性接触性皮炎167例(27.88%),在整个患者中所占比例最高。斑贴试验结果变应原呈阳性反应者有441例(73.62%)。阳性率由高到低排列的前6位变应原为:硫酸镍、硫柳汞、辛酸盐、芳香混合物、卡巴混合物和重铬酸钾。结论斑贴试验是寻找皮炎湿疹病因的有效手段。Objective To investigate the role of the environmental contact factors in the pathogenesis of eczema and the outcome.Methods Eczema patients were investigated by patch test and questionnaire interview.Results Five hundreds and ninety-nine eczema patients were recruited,and 167 cases（27.88%） were diagnosed as allergic contact dermatitis（ACD）,which was the most common.Of all patients,441 patients showed positive patch test results,which accounted for 73.62%.The most common allergens were nickel sulfate,thimerosal,octyl gallate,fragrance mix,carba mix and potassium dichromate,in descending order.Conclusion Patch test is a good method for screening pathogenesis of eczema.

关 键 词：湿疹 斑贴试验 

分 类 号：R758.23[医药卫生—皮肤病学与性病学] R758.14[医药卫生—临床医学]