围绝经期综合征中医证素与性激素水平的相关研究  

Correlational study on TCM syndrome elements and sex hormones in perimenopausal syndrome

作　　者：杨敏[1] 李灿东[1] 李红[2] 梁文娜[1] 

机构地区：[1]福建中医药大学,福州350108 [2]福建省立医院,福州350003

出　　处：《中华中医药杂志》2012年第2期366-368,共3页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家自然科学基金资助项目(No.30772697);福建省教育厅资助项目(No.JA10164);福建省自然科学基金项目(No.2010J01130)~~

摘　　要：目的:探讨围绝经期综合征常见中医证素与性激素水平的相关性。方法:选择174例围绝经期综合征患者,采用辨证要素积分的方法,通过对围绝经期综合征患者性激素指标的观察,研究围绝经期综合征中医证素与性激素水平的相关性。结果:①围绝经期综合征的病位证素主要以肝、肾为主;病性证素以阴虚、气滞、血虚为最多见;②E2与肾、血虚呈负相关;FSH与肾、血虚呈正相关;FSH/LH与肝、气滞呈正相关。结论:E2下降、FSH升高是肾虚形成的病理生理学基础之一,FSH/LH与肝郁密切相关。Objective： To disscus the relevance of TCM syndrome elements and sex hormones in perimenopausal syndrome.Methods： Choosing 174 perimenopausal syndrome patients,using the method of differentiation of syndrome elements,through the observation of sex hormones,to research relevance of TCM syndrome elements and sex hormones.Results： ①The main locations of perimenopausal syndrome are liver and kidney;Yin deficiency,Qi stagnation and blood deficiency are the main nature of disease.②E2 is negatively related to kidney and blood deficiency;FSH is positively related to kidney and blood deficiency;FSH/LH is positively related to liver and Qi stagnation.Conclusion： The decline of E2 and increase of FSH is one of the pathophysiological basis of deficiency of kidney,FSH/LH is closely related to the liver depression.

关 键 词：围绝经期综合征 证素 性激素 

分 类 号：R271.9[医药卫生—中西医结合]