布地奈德联合泰斯花粉阻隔剂治疗过敏性鼻炎的临床观察  

Clinical Observation of Budesonide Combined with Theiss Alergol Pollen Blocker in the Treatment of Allergic Rhinitis

作　　者：孙霄云[1,2] 康健[2] 陈冬[2] 马晓峰[2] 卢岩[2] 张慧颖[2] 张林[3] 刘堃[3] 

机构地区：[1]辽宁医学院,辽宁锦州121001 [2]辽宁医学院附属第一医院耳鼻喉科,辽宁锦州121001 [3]辽宁医学院护理学院,辽宁锦州121001

出　　处：《中国药房》2012年第8期697-699,共3页China Pharmacy

基　　金：辽宁省博士科研启动基金资助项目(20101063)

摘　　要：目的:观察布地奈德联合泰斯花粉阻隔剂治疗过敏性鼻炎的有效性和安全性。方法:收集整理门诊诊治的过敏性鼻炎患者98例,根据用药情况分为2组,对照组(47例)单纯应用布地奈德治疗,联合组(51例)应用布地奈德+泰斯花粉阻隔剂联合治疗,2组均连续用药14d。以症状积分下降指数评价疗效,观察2组布地奈德减量时间及不良反应发生情况。结果:联合组较对照组症状积分下降指数显著增加,布地奈德减量时间显著早于对照组,不良反应发生率亦显著低于对照组。结论:布地奈德联合泰斯花粉阻隔剂能更好的改善过敏性鼻炎症状,缩短患者布地奈德减量的时间,降低不良反应发生率。OBJECTIVE：To evaluate the efficacy and safety of budesonide combined with Theiss alergol pollen blocker in the treatment of allergic rhinitis and compare it with budesonide alone.METHODS：98 outpatient cases of allergic rhinitis were collected and separated into 2 groups according to the medicine administration.Control group with 47 cases were given budesonide only;Drug combination group with 51 cases were given Theiss and budesonide.All 2 groups were given relevant drugs for consecutive 14 days.We evaluated the clinical efficacy using symptom score reducing index,and analyzed the dosage decreasing time and adverse drug reactions of budesonide.RESULTS：Symptom score reducing index in drug combination group increased significantly,compared with control group.Dosage decreasing time of budesonide in drug combination group was significantly earlier than control group.The incidence of adverse drug reactions in drug combination group was significantly lower than control group.CONCLUSIONS：Budesonide combined with Theiss alergol pollen blocker could give a better way to ameliorate clinical symptom of allergic rhinitis.Combined use of theiss alergol pollen blocker and budesonide could put forward the dosage decreasing time of budesonide and decrease the incidence of adverse drug reactions.

关 键 词：布地奈德 泰斯花粉阻隔剂 过敏性鼻炎 临床疗效 

分 类 号：R765.21[医药卫生—耳鼻咽喉科]