白芍总苷联合补骨脂注射液治疗寻常型银屑病的疗效观察  

Efficacy Observation of TGP Combined with Fructus Psoraleae Injection in the Treatment of Psoriasis Vulgaris

作　　者：杜宇[1] 廖勇梅[1] 钟桂书[1] 颜丹[1] 熊霞[1] 

机构地区：[1]泸州医学院附属医院皮肤科,四川泸州646000

出　　处：《中国药房》2012年第8期707-708,共2页China Pharmacy

摘　　要：目的:观察白芍总苷(TGP)联合补骨脂注射液治疗寻常型银屑病的疗效和安全性。方法:将189例寻常型银屑病患者分为2组,治疗组97例,口服TGP联合应用补骨脂注射液;对照组92例,仅应用补骨脂注射液。2组疗程均为4周。观察2组治疗效果及不良反应发生情况。结果:治疗组总有效率为88.66%,明显高于对照组(67.40%)。治疗组治疗后银屑病面积与严重程度指数(PASI)评分亦显著低于对照组。2组均未见严重不良反应发生。结论:TGP联合补骨脂注射液治疗寻常型银屑病有较好临床疗效,并可减少补骨脂注射液的副作用。OBJECTIVE：To observe the therapeutic efficacy and safety of total glucosides of paeony（TGP） combined with Fructus psoraleae injection in the treatment of psoriasis vulgaris.METHODS：189 cases of psoriasis patients were randomized into 2 groups：treatment group with 97 patients was treated with oral TGP combined with Fructus psoraleae injection;control group with 92 sufferers was given Fructus psoraleae injection alone.Observation duration lasted for 4 weeks.Therapeutic efficacy and adverse drug reaction of 2 groups were observed.RESULTS：The total effective rate for treatment group were 88.66% respectively;while that for the control group was 67.40%,thus the former was obviously higher than the latter（P0.05）.The PASI score in treatment group was obviously lower than in control group after treatment.No obvious adverse drug reaction was found in 2 groups.CONCLUSIONS：TGP combined with Fructus psoraleae injection has comparatively desirable clinical efficacy towards psoriasis vulgaris and can reduce side effects of Fructus psoraleae injection.

关 键 词：银屑病 白芍总苷 补骨脂注射液 

分 类 号：R758.63[医药卫生—皮肤病学与性病学]