Analgesic action of suspended moxibustion in rats with chronic visceral hyperalgesia correlates with enkephalins in the spinal cord  

作　　者：Tao Yi Li Qi Huangan Wu Xiaopeng Ma Huirong Liu Xiaomei Wang 

机构地区：[1]Shanghai Institute of Acupuncture-Moxibustion and Meridians, Shanghai University of Traditional Chinese Medicine, Shanghai 200030,China [2]E-institute of Shanghai Municipal Education Committee, Shanghai University of Traditional Chinese Medicine, Shanghai 200030, China

出　　处：《Neural Regeneration Research》2012年第3期219-222,共4页中国神经再生研究（英文版）

基　　金：supported by the National Basic Research Program of China (973 Program) (No. 2009CB522900);the National Natural Science Foundation of China (No. 30973783);the Shanghai Leading Academic Discipline Project (No. S30304)

摘　　要：Rats that modeled chronic visceral hyperalgesia received suspended moxibustion at bilateral Tianshu （ST25） and Shangjuxu （ST37） once daily over a period of 7 days. Results show that suspended moxibustion significantly depressed abdominal withdrawal reflex scores and increased enkephalin concentration in the spinal cord. The experimental findings suggest that spinal enkephalins contributed to the analgesic effect of suspended moxibustion in rats with chronic visceral hyperalgesia.Rats that modeled chronic visceral hyperalgesia received suspended moxibustion at bilateral Tianshu （ST25） and Shangjuxu （ST37） once daily over a period of 7 days. Results show that suspended moxibustion significantly depressed abdominal withdrawal reflex scores and increased enkephalin concentration in the spinal cord. The experimental findings suggest that spinal enkephalins contributed to the analgesic effect of suspended moxibustion in rats with chronic visceral hyperalgesia.

关 键 词：suspended moxibustion chronic visceral hyperalgesia ENKEPHALINS irritable bowel syndrome 

分 类 号：Q426[生物学—神经生物学] S859.791[生物学—生理学]