家族性心房纤颤的遗传分析  

Genetic Analysis of Familial Atrial Fibrillation

作　　者：洪昌明[1] 郑强荪[2] 舒青[3] 

机构地区：[1]中国人民解放军总医院老年心血管二科,北京市100853 [2]第四军医大学附属唐都医院心内科 [3]第四军医大学遗传与发育生物学教研室

出　　处：《中国全科医学》2012年第2期182-183,共2页Chinese General Practice

摘　　要：目的分析一个家族性心房纤颤家系的遗传学特点。方法查此家族成员的病史,记录心电图,绘制家系图。结果该家系3代19人中有6人患有心房纤颤。结论经过遗传分析,认为该家系属于常染色体显性遗传。Objective To investigate the genetic characters of a pedigree′s familial atrial fibrillation. Methods The family members were investigated about the formal medical history and ECGs were recorded in order to draw the pedigree diagram. Results 6 out of 19 among three generations suffered from atrial fibrillation. Conclusion Genetic analysis concluded that this disease was caused by autosomal dominant inheritance.

关 键 词：心房颤动 系谱 常染色体显性遗传 

分 类 号：R541[医药卫生—心血管疾病]