MR弥散加权成像诊断股骨头坏死  

MR diffusion imaging in diagnosis of femoral head necrosis

作　　者：董越[1] 王琰[1] 王绍武[1] 郑淞文[1] 姜原[1] 王茹欣[1] 宁殿秀[1] 宋清伟[1] 

机构地区：[1]大连医科大学附属第一医院放射科,辽宁大连116011

出　　处：《中国医学影像技术》2012年第2期352-355,共4页Chinese Journal of Medical Imaging Technology

基　　金：国家自然科学基金(30801061);辽宁省教育厅科学技术研究项目(2008155)

摘　　要：目的探讨MR DWI在股骨头坏死诊断及分期中的价值。方法应用MR SE-EPI-DWI序列对34例股骨头坏死患者共40个髋关节[根据Steinberg分期分为I～Ⅱ期(第1组)、Ⅲ～Ⅳ期(第2组)、Ⅴ～Ⅵ期(第3组)]及90名健康志愿者共180个髋关节进行图像采集,b值分别选取300、500、700s/mm2。应用Functool软件进行分析,得到ADC图。选取ROI为100mm2,测量双侧股骨头的ADC值,并进行统计学分析。结果 b值为300、500、700s/mm2时,股骨头坏死患者股骨头的ADC均值分别为(13.00±2.54)×10-4 mm2/s、(10.73±3.10)×10-4 mm2/s、(8.77±1.55)×10-4 mm2/s,正常股骨头的ADC均值分别为(3.63±1.34)×10-4 mm2/s、(1.87±0.76)×10-4 mm2/s、(1.49±0.53)×10-4 mm2/s,差异均有统计学意义(P均<0.05)。第1组股骨头坏死区ADC值最小,第2组ADC值最大,而第3组ADC值又减小,差异有统计学意义(P<0.05)。结论 MR DWI可以清晰显示股骨头坏死的病变区域,ADC值对于区分正常及病变区域、指导股骨头坏死分期有一定价值。Objective To assess the value of MR DWI in diagnosis and staging of femoral head necrosis.Methods Thirty-four patients with femoral head necrosis（40 hip joints） and 90 healthy volunteers（180 hip joints） were included.The patients were divided into 3 groups according to Steinberg stage（Ⅰ—Ⅱ of group 1,Ⅲ—Ⅳ of group 2,Ⅴ—Ⅵ of group 3）.SE-EPI-DWI was performed to obtain images with b values of 300,500 and 700 s/mm2,respectively.ADC maps were obtained with Functool software.ADC values of femoral head were measured using 100 mm2 ROIs,and then were statistically analyzed.Results With b value of 300,500 and 700 s/mm2,the mean ADC value of femoral head necrosis was（13.00±2.54）×10-4 mm2/s,（10.73±3.10）×10-4 mm2/s and（8.77±1.55）×10-4 mm2/s,respectively,while the mean ADC value of healthy femoral heads was（3.63±1.34）×10-4 mm2/s,（1.87±0.76）×10-4 mm2/s,（1.49±0.53）×10-4 mm2/s.There were significant statistical differences in ADC values of normal femoral head and femoral head necrosis（all P〈0.05）.ADC values of femoral head necrosis in group 1 were minimum,and were maximum in group 2,then reduced in group 3（P〈0.05）.Conclusion DWI can display the femoral head necrosis clearly.ADC values contribute to distinguishing the normal and pathological regions of femoral head,as well as staging necrosis of the femoral head.

关 键 词：磁共振成像 股骨头坏死 表观弥散系数 

分 类 号：R445.2[医药卫生—影像医学与核医学] R681[医药卫生—诊断学]