DYNAMIC ANALYSIS OF FLUID-STRUCTURE INTERACTION OF ENDOLYMPH AND CUPULA IN THE LATERAL SEMICIRCULAR CANAL OF INNER EAR  

作　　者：WU Cai-qin HUA Cheng YANG Lin DAI Pei-dong ZHANG Tian-yu WANG Ke-qiang 

机构地区：[1]Department of Mechanics and Engineering Science, Fudan University, Shanghai 200433, China [2]Eye and ENT Hospital of Fudan University, Shanghai 200031, China [3]Cardiovascular Disease Institute, Zhongshan Hospital of Fudan University, Shanghai 200032, China

出　　处：《Journal of Hydrodynamics》2011年第6期777-783,共7页水动力学研究与进展B辑（英文版）

基　　金：supported by the National Natural Science Foundation of China (Grant No. 30971528);the Shanghai Committee of Science and Technology of China (Grant No.10ZR1403500);supported by the Graduate Innovation Fund of Fudan University (Grant No.EYH2126023)

摘　　要：The semicircular canals, composed of lateral, anterior and posterior canals in the inner ear, are the sensors of equilibrium during head rotation movements in the three-dimensional space. Semicircular canals are filled with endolymph confined by the cupula. The study of the relationship between endolymph flow and cupular deformation is important in revealing the semicircular canals biomechanical behavior. To date, there are few studies focusing on the transient endolymph flow and cupular deformation in response to a head rotation motion. The lateral semicircular canal is mainly responsible for the sense of the horizontal rotation movement. In order to figure out the intricate dynamics in the lateral semicircular canal during the head rotation motion, the time evolutions of both endolymph flow and cupular deformation are analyzed in this article by using a fully coupled fluid-structure interaction model. It is shown that the cupular deformation provides cues for understanding the physiology of sensing the head rotation.The semicircular canals, composed of lateral, anterior and posterior canals in the inner ear, are the sensors of equilibrium during head rotation movements in the three-dimensional space. Semicircular canals are filled with endolymph confined by the cupula. The study of the relationship between endolymph flow and cupular deformation is important in revealing the semicircular canals biomechanical behavior. To date, there are few studies focusing on the transient endolymph flow and cupular deformation in response to a head rotation motion. The lateral semicircular canal is mainly responsible for the sense of the horizontal rotation movement. In order to figure out the intricate dynamics in the lateral semicircular canal during the head rotation motion, the time evolutions of both endolymph flow and cupular deformation are analyzed in this article by using a fully coupled fluid-structure interaction model. It is shown that the cupular deformation provides cues for understanding the physiology of sensing the head rotation.

关 键 词：fluid-structure interaction ENDOLYMPH cupula finite element method 

分 类 号：O629.711[理学—有机化学] S945[理学—化学]