急性心肌梗死患者肾素-血管紧张素Ⅱ-醛固酮活性变化  

Change and its clinical effects of renin-angiotension-aldosterone in patients with acute myocardial infarction

作　　者：陈志媛[1] 周国胜[2] 薛鸿群[1] 牛宝松[1] 狄长春[2] 陈亚君[1] 李清萍[2] 

机构地区：[1]河南省焦作市第二人民医院老年病科,河南焦作454001 [2]河南省焦作市第二人民医院核医学科,河南焦作454001

出　　处：《中国现代医生》2012年第5期148-149,共2页China Modern Doctor

摘　　要：目的探讨急性心肌梗死(AMI)患者血清肾素-血管紧张素-醛固酮系统(RASS)的变化及其临床意义。方法用放射免疫法检测30例心肌梗死患者PRA、AngⅡ和ALD血清含量并与正常对照组35例比较。结果急性心肌梗死组PRA、AngⅡ和ALD明显高于对照组(P<0.05),差异有统计学意义。结论 RASS参与心肌梗死的发生和发展,测定PRA、AngⅡ和ALD可作为判断病情的一个指标,有助于心肌梗死的早期诊断和治疗。Objective To investigate the change of renin-angiotension-aldosterone in patients with acute myocardial infarction and clinical effects. Methods Rennin, angiotension Ⅱ and aldosterones in 30 patients with acute myocardial infarction were measured with radioimrnunoassay and compared with 35 individuals of control. Results Renin, angiotension Ⅱ and aldosterones in patients with acute myocardial infarction were higher statistically than 35 individuals of control （P 〈 0.05）. Conclusion Renin, angiotension Ⅱ and aldosterone may act as an important indicator while acute myocardial infarction takes place and progresses, and can evaluate patients＇ conditions, and is helpful for diagnosis and treatment of acute my- ocardial infarction.

关 键 词：急性心肌梗死 肾素-血管紧张素Ⅱ-醛固酮系统 

分 类 号：R542.2[医药卫生—心血管疾病]