GC-MS法对怀山药饮片中六种农药残留量的测定  

Determination of 6 Kinds of Pesticides Residue in Dioscoreae Rhizoma Slices by GC-MS

作　　者：蒋以号[1,2] 刘伟 曹晖 于留荣[1,4] 向飞军 

机构地区：[1]康美药业股份有限公司,广东普宁515341 [2]南昌大学环境与化学工程学院,江西南昌330031 [3]国家中药现代化工程技术研究中心,广东珠海519100 [4]南方医科大学,广东广州510627

出　　处：《中药材》2011年第12期1841-1843,共3页Journal of Chinese Medicinal Materials

摘　　要：目的:同时测定山药生品饮片、麸炒饮片和硫磺熏蒸饮片中的有机磷、有机氯和拟除虫菊酯类6种农药残留量。方法:样品用乙腈提取并经净化后供气相色谱-质谱仪(GC-MS)分析。采用选择离子扫描方式,外标法定量。结果:6种农药在0.01～0.5μg/mL之间线性关系良好,平均回收率为87.5%～95.5%,检出限为0.002～0.005μg/g。在3个样品中均检出了有机氯和拟除虫菊酯类农药,对硫磷未检出。结论:麸炒与硫熏对山药中农药残留无明显影响;本方法灵敏、准确,适用于山药中农药多残留的分析。Objective：To determine the 6 residues including organophosphorus,organochlorinated and pyrethroid pesticides simultaneously in crude yam slices,yam slices stir-fried with bran and sulfur fumigation yam.Methods： The compounds were ready for GC-MS analysis after being extracted with acetonitrile and purified.Determinations were performed with selected ion monitoring mode and external standard method was adopted in the quantificaticon.Results： The contents of 6 kinds pesticides residue had good linear correlation with the peak area in the rang of 0.01~0.5μg/mL.The average recoveries of 6 kinds pesticides residue were 87.5 %~95.5%.The method detection limits ranged from 0.002~0.005 μg/g.Organochlorine and pyrethroid pesticides were detected in the three samples except the parathion residue.Conclusion： Stir-fried with bran and sulphur fumigation had nearly no effects on the pesticides residue in yam.The method is sensitive and accurate and can be used in determination of multiresidual pesticides residue in yam.

关 键 词：山药饮片 农药 残留 气质联用法 

分 类 号：R282.2[医药卫生—中药学]