球花牛奶菜甾体成分研究  

STUDIES ON THE CONSTITUENTS FROM MARSDENIA GLOBIFERA

作　　者：邱声祥[1] 张壮鑫[2] 周俊[2] 

机构地区：[1]中国医药研究开发中心,北京102206 [2]中国科学院昆明植物研究所,昆明650204

出　　处：《Acta Botanica Sinica》1990年第12期936-942,共7页Acta Botanica Sinica（植物学报：英文版）

摘　　要：从萝藦科植物球花牛奶菜(Marsdenia globifera)的粗甙水解物中,反复硅胶柱正相层析及 Rp-8,Rp-18反相层析共分离到8个 C_(21)甾体化合物,用光谱及化学方法推定了结构,分别是已知化合物肉珊瑚甙元(sarcostin,Ⅰ),吉马甙元(gymnemarsgenin,Ⅳ),本波甙元(penupogenin,Ⅵ),20-氧-桂皮酰肉珊瑚甙元(20-O-cinnamoylsarcostin,Ⅴ),异林里奥酮(isolineolon,Ⅷ)和新化合物球花牛奶甙元甲(20-O-Benzoylsarcostin,Ⅱ),球花牛奶甙元乙(12-O-Benzoylsarcostin,Ⅲ)。本文还对上述各化合物的碳谱作了系统指定。Two novel C-21 steroidal aglycones named marsglogenin-A(Ⅱ)and marsglogenin-B(Ⅲ) as well as six known compounds sarcostin(Ⅰ),gymnemarsgenin(Ⅳ),20-O-cinnamoylsarco- stin(Ⅴ),penupogenin(Ⅵ),gagaminin(Ⅶ)and isolineolcn(Ⅷ)were isolated from the acid hydrolysate of the crude glycoside extracted with ethanol from the stem of Marsdenia globi- fera(Asclepiadaceae).The structures of marsglogenin-A and marsglogenin-B were deduced as 20-O-benzoylsarcostin and 12-O-benzoylsarcostin on the bases of chemical and spectral evi- dences respectively.

关 键 词：球花牛奶菜 甾体 

分 类 号：Q946[生物学—植物学]