Comparison of Clinical Efficacy of Three Surgical Methods in the Treatment of Pterygium  

作　　者：Chaoming Yu Weiliang Liang Yongyu Huang Weiwen Guan 

机构地区：[1]Department of Ophthalmology, Kaiping Center Hospital, Guangdong Province, China

出　　处：《Eye Science》2011年第4期193-196,共4页眼科学报（英文版）

摘　　要：Purpose:To investigate and compare the efficacy of amniotic membrane transplantation,corneal limbus stem cell conjunctival transplantation and pedicle conjunctival flap transposition in the treatment of pterygium.Methods:.A total of 155 patients with pterygium were retrospectively analyted:.53 cases who received amniotic membrane transplantation,.41 who underwent corneal limbus stem cells conjunctival transplantation,and 61 patients who had pedicle conjunctival flap transposition.Results:Patients in the three groups had no significant differences in terms of age,times since surgery,or extent of pterygium extension onto the cornea (F:1.194,0.639,0.140 respectively;all P>0.05)..A total of 137 out of 155 patients (88.4%) completed 6 months of follow up.The recurrence rates of pterygium for the three surgeries (amniotic membrane transplantation,.corneal limbus stem cells conjunctival transplantation and pedicle conjunctival flap transposition) were 14.6%,13.9% and 7.7%,respectively.No significant difference was identified when comparing the recurrence rate between any two groups(X2:.0.008,1.211 and 0.890;P:0.593,0.218 and 0.276)..Five patients presented with postoperative complications,.including 3 cases of sub-conjunctival hemorrhage,1 case of amniotic membrane dissolution,and 1 case of conjunctival cyst,accounting for 3.64% of all participants.Conclusion:These three surgical methods are equally effective in preventing the recurrence of pterygium after excision.Purpose：To investigate and compare the efficacy of amniotic membrane transplantation,corneal limbus stem cell conjunctival transplantation and pedicle conjunctival flap transposition in the treatment of pterygium.Methods：.A total of 155 patients with pterygium were retrospectively analyted：.53 cases who received amniotic membrane transplantation,.41 who underwent corneal limbus stem cells conjunctival transplantation,and 61 patients who had pedicle conjunctival flap transposition.Results：Patients in the three groups had no significant differences in terms of age,times since surgery,or extent of pterygium extension onto the cornea （F：1.194,0.639,0.140 respectively;all P〉0.05）..A total of 137 out of 155 patients （88.4%） completed 6 months of follow up.The recurrence rates of pterygium for the three surgeries （amniotic membrane transplantation,.corneal limbus stem cells conjunctival transplantation and pedicle conjunctival flap transposition） were 14.6%,13.9% and 7.7%,respectively.No significant difference was identified when comparing the recurrence rate between any two groups（X2：.0.008,1.211 and 0.890;P：0.593,0.218 and 0.276）..Five patients presented with postoperative complications,.including 3 cases of sub-conjunctival hemorrhage,1 case of amniotic membrane dissolution,and 1 case of conjunctival cyst,accounting for 3.64% of all participants.Conclusion：These three surgical methods are equally effective in preventing the recurrence of pterygium after excision.

关 键 词：手术方法 疗效比较 治疗 角膜缘干细胞 羊膜移植 肉 临床 复发率 

分 类 号：S858.292[农业科学—临床兽医学] S858.315.1[农业科学—兽医学]