静脉注射不同浓度戊巴比妥钠对兔麻醉死亡率的影响  

Effect of Different Concentration of Pentobarbital Sodium Injected Intravenously on Mortality of Rabbits

作　　者：周洁[1] 张稳燕[1] 孟勇[1] 

机构地区：[1]徐州医学院机能实验室,徐州221004

出　　处：《实验动物科学》2011年第6期67-68,共2页Laboratory Animal Science

摘　　要：目的在麻醉效果相同的条件下,探讨麻醉死亡率更低的戊巴比妥钠使用浓度。方法选用新西兰家兔(2～3kg),雌雄各半,分为1%戊巴比妥钠组和3%戊巴比妥钠组,观察比较两组麻醉效果和死亡率。结果 1%和3%戊巴比妥钠组麻醉效果无差异,而1%组死亡率更低,与3%组比较有显著差异。结论可将常规使用3%戊巴比妥钠进行家兔静脉麻醉改为使用1%的戊巴比妥钠,两者麻醉效果相当,而后者死亡率更低。Objective To observe which concentration of pentobarbital sodium induces lower mortality when obtaining the same anesthetic effect in rabbits. Methods New Zealand rabbits were divided into 1% pentobarbital sodium group and 3% pentobarbital sodium group. The anesthetic effects and mortality were observed. Results There is no significant difference of anesthetic effects between the two groups, but 1% pentobarbital sodium group achieved a lower mortality （ P 〈 0. 05 ）. Conclusions We should replace 3% pentobarbital sodium with 1% pentobarbital sodium when anesthetizing rabbits because 1% pentobarbital sodium induces lower mortality and equal anesthetic effect compared with 3% pentobarbital sodium.

关 键 词：兔 麻醉 戊巴比妥钠 

分 类 号：Q95-331[生物学—动物学]