银掺杂聚L-苏氨酸修饰电极的制备及对多巴胺的测定  

PREPARATION OF SILVER DOPED POLY(L-THREONINE) MODIFIED ELECTRODE AND DETERMINATION OF DOPAMINE

作　　者：赵庆侠[1] 马伟[1] 孙登明[1] 

机构地区：[1]淮北师范大学化学与材料科学学院,安徽淮北235000

出　　处：《井冈山大学学报（自然科学版）》2011年第6期27-32,共6页Journal of Jinggangshan University (Natural Science)

基　　金：安徽省高校省级自然科学研究重点项目(KJ2011A255)

摘　　要：利用循环伏安法,研究了银和L-苏氨酸在玻碳电极表面电化学聚合的条件,制备了银掺杂聚L-苏氨酸修饰电极。并研究了多巴胺在修饰电极上的电化学行为,建立了测定多巴胺的新方法。在pH=6.5磷酸盐缓冲溶液中,扫描速率为20mV/s,多巴胺在修饰电极上产生一对明显的氧化还原峰,峰电位分别为Epa=0.218V,Epc=0.189V。用示差脉冲伏安法测定时,峰电流与多巴胺浓度分别在8.00×10-7～1.00×10-5和1.00×10-5～1.00×10-4mol/L范围内呈良好的线性关系,检出限为1.0×10-7mol/L。用于药物中多巴胺的测定,结果满意。A silver doped poly（L-threoninie） modified electrode was prepared by electrochemical immobilization of silver and L-threonine on a glassy carbon electrode surface.The polymerization conditions and the electrochemical behavior of dopamine were studied.A novel voltammetric method was proposed for the determination of dopamine.In pH 6.5 phosphate buffer solution,a pair of redox peaks were observed at Epa = 0.218V and Epc = 0.189 V（vs Ag/AgCl） at a scan rate of 20 m V/s.By differential pulse voltammetry,the oxidation peak current of dopamine was proportional to the concentration in a range of 8.00×10-7～1.00×10-5mol/L and 1.00×10-5～1.00×10-4 mol/L.The detection limit was 1.0×10-7 mol/L.The method was applied to the determination of dopamine in drug with satisfactory results.

关 键 词：银掺杂 L-苏氨酸 多巴胺 修饰电极 循环伏安法 示差脉冲伏安法 

分 类 号：O657.1[理学—分析化学]