乳果糖口服溶液联合甘油灌肠剂治疗老年卧床患者顽固性便秘25例  

Lactulose Oral Solution Combined with Glycerol Enema in Treating 25 Cases of Bedridden Elderly Intractable Constipation

作　　者：秦燕[1] 周晓兵[1] 郑瑾[1] 高洁[1] 

机构地区：[1]中国人民解放军总医院南楼心血管二科,北京100853

出　　处：《中国药业》2012年第3期60-61,共2页China Pharmaceuticals

摘　　要：目的观察乳果糖口服溶液口服联合甘油灌肠剂纳肛用于改善老年卧床患者便秘的效果。方法将50例老年卧床患者随机均分成试验组和对照组,试验组给予乳果糖口服溶液口服联合甘油灌肠剂纳肛,对照组单用甘油灌肠剂纳肛,观察并记录排便效果和腹胀症状缓解情况。结果试验组改善排便效果和腹胀缓解的总有效率均为92.00%,明显高于对照组的80.00%和64.00%,差异有统计学意义(P<0.05)。结论乳果糖口服溶液口服联合甘油灌肠剂纳肛改善老年卧床患者顽固性便秘的效果优于单用甘油灌肠剂纳肛。Objective To evaluate the effect of Lactulose Oral Solution with Glycerol Enema in treating bedridden elderly intractable constipation. Methods Fifty cases of bedridden elderly intractable constipation were randomly divided into two groups. Tweenty-five cases in the treatment group were given Lactulose Oral Solution with Glycerol Enema, while 25 cases in the control group accepted Glycerol Enema alone. The symptoms including defecation and abdominal distension were observed and recorded after treatment. Results After 9- week treatment, the total effects of improving defecation and abdominal distension was 92.00% in the treatment group, which was significantly higher than 80.00% and 64. 00% in the control group with statistical difference （P 〈 0. 05） Conclusion Lactulose Oral Solution combined with Glycerol Enema is superior to Glycerol Enema alone in improving intractable constipation in bedridden el- derly patients.

关 键 词：老年人 卧床 便秘 甘油灌肠剂 乳果糖 

分 类 号：R969.4[医药卫生—药理学] R977.6[医药卫生—药学]