“三才刺、透灸”并用对肾绞痛大鼠前列腺素的影响  

Influence with Combination Treatment of Three-level Acupuncture and Penetrating Moxibustion on Prostaglandin in Rats with Renal Colic

作　　者：王巍[1] 张洁[1] 

机构地区：[1]辽宁中医药大学,辽宁沈阳110032

出　　处：《中国中医急症》2012年第2期218-219,225,共3页Journal of Emergency in Traditional Chinese Medicine

基　　金：辽宁省教育厅创新团队课题(2008T120)

摘　　要：目的观察不同针灸并用法对肾绞痛大鼠前列腺素的影响差异,确立取得最佳效应的特异针灸手法及其机理。方法采用1%乙二醇加1%氯化铵水作为诱石剂建立草酸钙结石致大鼠肾绞痛模型,观察不同针灸并用法对肾绞痛大鼠血、尿中前列环素(PGI2)和血栓素(TXA2)的水平变化的影响。结果与模型组比较,"三才刺、透灸"并用法和常规针灸并用法均可降低血、尿中PGI2和TXA2的水平,但"三才刺、透灸"并用法更显著。结论 "三才刺、透灸"并用法对肾绞痛大鼠的镇痛作用优于常规针灸并用法,其作用机制可能是降低肾绞痛大鼠血、尿中PGI2和TXA2的水平,与选穴可能关系不密切。Objective： To observe the differences among several combination treatments of acupuncture and moxibustion and to establish the operation method and its mechanism with best effect in combination treatments of acupuncture and moxibustion.Methods： The model of the renal colic rat was established by the calcium oxalate calculus which was induced by the 1% glycol with 1% ammonium chloride.After being used the several methods of combination treatment of acupuncture and moxibustion,these indices were detected including the PGI2 and the TXA2 in these rats＇ blood and urine.Results： Compared with the model group,levels in the PGI2 and the TXA2 were decreased by the combination treatment of three-level acupuncture and penetrating moxibustion and the normal combination of acupuncture and moxibustion.However,the effect of the previous method was more remarkable.Conclusion： The analgesic effect of the combination treatment of three-level acupuncture and penetrating moxibustion is better than that of the normal combination of acupuncture and moxibustion.Its mechanism could be the reduction in levels of the PGI2 and the TXA2 in the blood and the urine.The effect of the combination treatment of three-level acupuncture and penetrating moxibustion is not close to the points selections of it.

关 键 词：针灸疗法 肾绞痛 电针 艾灸 前列环素 血栓素 

分 类 号：R245[医药卫生—针灸推拿学]