冠心病合并慢性肾脏病患病率及危险因素调查  

The prevalence and risk factors of coronary heart disease combined with chronic kidney disease

作　　者：桑晓红[1] 闫淑芳[2] 孙岩[1] 

机构地区：[1]新疆医科大学第一附属医院肾病科,乌鲁木齐830054 [2]新疆克拉玛依市中心医院肾病风湿科

出　　处：《中华内科杂志》2012年第2期123-126,共4页Chinese Journal of Internal Medicine

摘　　要：目的 探讨住院冠心病患者合并慢性肾脏病的患病情况及危险因素.方法 对2009年1-12月在新疆医科大学第一附属医院住院确诊为冠心病的患者,进行慢性肾脏病的患病率及危险因素回顾性调查.结果 在资料完整的960例冠心病人群中,蛋白尿患病率为11.04％；肾小球滤过率（eGFR）下降的患病率为10.52％；慢性肾脏病总的患病率为16.77％,男性为16.67％,女性为17.11％,男、女患病率差异无统计学意义（P＞0.05）.经多因素logistic回归分析表明：糖尿病（OR2.60,95％CI 1.17 ～3.29）是冠心病合并蛋白尿的危险因素,年龄增加10岁（OR 1.55,95％ CI 1.31～1.83）、糖尿病（OR 1.69,95％ CI 1.15 ～2.47）、高胆固醇血症（OR2.89,95％CI 1.49 ～5.61）和高尿酸血症（OR 1.49,95％ CI0.96 ～2.33）是冠心病合并慢性肾脏病的危险因素.结论 冠心病合并慢性肾脏病的患病率高,应引起重视.Objective To investigate the prevalence rate and risk factors of inpatients with coronary atherosclerotic heart disease （CHD） combined chronic kidney disease （CKD）.Methods All people who underwent CHD combined CKD in CHD department of the First Affiliated Hospital of Xinjiang Medical University during January to December 2009 were enrolled in the retrospective study.Results A total of 960 hospitalized patients with CHD were enrolled during the observation period. The prevalence of proteinuria and reduced eGFR were 11.04% and 10.52%,respectively.The total CKD prevalence rate was 16.77%,with male of 16.67% and female of 17.11%.There was no significant difference in prevalence rate between male and female（ P 〉 0.05 ）.The multi-factors logistic regression analysis showed that diabetes mellitus（OR 2.60,95%CI 1.17-3.29） was risk factor for CHD combined proteinuria.Ten-years older in age （ OR 1.55, 95%CI 1.31-1.83 ）, diabetes mellitus （ OR 1.69, 95%CI 1.15-2.47 ）,hypercholesterolemia （ OR 2.89,95% CI 1.49-5.61 ）,and hyperuricemia（ OR 1.49,95% CI 0.96-2.33 ）were risk factors for CHD combined CKD. Conclusion More attention should be paid to the high prevalence of CHD combined CKD.

关 键 词：慢性肾脏病 冠心病 患病率 危险因素 

分 类 号：R692[医药卫生—泌尿科学]