18例伪膜性肠炎内镜及临床特点分析  

Endoscopic and clinical analysis of 18 patients with Pseudomanbranous Colonitis

作　　者：吴利娟[1] 赵勇洁[1] 董彩红[1] 乔娜娜[1] 

机构地区：[1]河南科技大学一附院,河南洛阳471003

出　　处：《中国当代医药》2012年第2期180-180,182,共2页China Modern Medicine

摘　　要：目的:探讨伪膜性肠炎(pseudrmembranous colitis,PMC)患者的临床表现及内镜特点,提高诊治水平。方法:对本院6年来诊治的18例PMC患者的临床资料进行回顾性分析。结果:PMC是一种长期应用抗生素的并发症,易发生在长期慢性疾病、年龄大、体质差及抗生素应用不规范的患者,表现为腹泻、腹痛、血便等症状,结肠镜检查发现多数患者伪膜呈连续性或散在性分布。结论:抗生素不规范应用是主要病因,尤其老年及重症患者,结肠镜检查是诊断PMC快速而可靠的方法,治疗应停用相关抗生素口服甲硝唑、万古霉素和益生菌是治疗PMC有效方法。Objective： To analyze the clinical manifestationand endoscopic features of PMC,and to improve the level of diagnosis and treatment. Methods： The clinical data of 18 cases of patients with PMC was analyzed retrospectively in recent 6 years. Results： Pseudomembranous colitis was a common intestinal complication in old patients with chronic diseases,weak constitution,postoperation under the abuse of antibiotics. Clinical symptom were diarrhea, abdominal pain, bloody stool, tenesmus. Endoscopy showed the continuous or diffused presence of pseudomembranes on intestinal mucosa.Conclusion： Antibiotic abusing is the main cause of PMC. The diagnosis can be confirmed by the colonoscopy features simply and reliably,and it would be cured successfully with oral vancomycin, metronidazole and probiotics after withdrawal of antibiotics promptly.

关 键 词：伪膜性肠炎 临床特点 结肠镜 临床分析 

分 类 号：R516.1[医药卫生—内科学]