复方桑黄颗粒中总黄酮成分提取工艺研究  

Studies on extraction of total flavonoids of compound Sanghuang granules

作　　者：陈雨微[1] 张红玉[1] 宋棋芬[1] 徐茂义[1] 黄越燕[1] 

机构地区：[1]嘉兴学院医学院,浙江嘉兴314001

出　　处：《中国医药科学》2012年第3期152-153,共2页China Medicine And Pharmacy

基　　金：浙江省嘉兴市科技局资助项目(2010AY1066);2010年度浙江省大学生科技创新活动计划资助项目(2010R417005)

摘　　要：目的优化复方桑黄颗粒的提取工艺。方法以正交试验表对复方桑黄颗粒中总黄酮成分醇提工艺的影响因素进行考察,优选工艺条件。结果优选提取工艺为20倍量的70%乙醇,回流提取3次,总黄酮提取率为30.29%,出膏率为10.39%。结论该提取工艺条件稳定,重现性好,可为复方桑黄颗粒的大生产提供参考依据。Objective To optimize the extraction process for compound sanghuang granules. Methods Factors affecting the ethanol extraction process to flavonoids of compound sanghuang granules was studied,the best preparation technological conditions was screened by orthogonal design. Results The optimal extraction technique conditions were as follows：20 times of amount of 70% alcohol,extracted for 3 times,each time far 2 hours. High yield of extraetum （30.29%） and high content of fiavonids （10.39%） are obtained with the present technology. Conclusion The extracting melhod are stables and replicable,which can provide reference for preparation of compound sanghuang granules.

关 键 词：桑叶 总黄酮 提取工艺 正交试验 

分 类 号：R284.2[医药卫生—中药学]