纳米级超声造影剂的研究现状与问题  

Status and problems of nanoscale ultrasound contrast agent

作　　者：胡洁[1] 吴凤林[1] 

机构地区：[1]南方医科大学南方医院超声科,广东广州510515

出　　处：《中国介入影像与治疗学》2012年第2期139-142,共4页Chinese Journal of Interventional Imaging and Therapy

摘　　要：随着纳米级超声造影剂的发展,超声成像已经步入生物纳米技术与超声分子影像结合的新阶段。纳米级超声造影剂在分子影像和靶向药物输送方面具有独特的优势。目前研究较多的是纳米级液态氟烷乳剂、纳米级微泡造影剂和纳米级脂质体造影剂,本文对此3种纳米级超声造影剂的发展现状及问题进行综述。With the development of nanoscale ultrasound contrast agent,ultrasound imaging has entered a new era that combining biomedical nanotechnology with molecular ultrasound imaging.Nanoparticle-based contrast agents are quickly becoming valuable and attractive tools for molecular imaging and targeted drug-delivery application,including perfluorocarbon emulsion nanoparticles,nanobubbles and liposomal agents.The current development,potential disadvantages as well as future perspectives of nanoscale ultrasound contrast agents were reviewed in this article.

关 键 词：造影剂 分子成像 纳米技术 超声检查 

分 类 号：R310[医药卫生—基础医学]