46例2型糖尿病患者窦性心率震荡研究  

Analysis of the sinus heart rate turbulence in 46 patients with type 2 diabetes mellitus

作　　者：王雁[1] 杜新超[1] 陈秋[1] 范玉欢[1] 

机构地区：[1]郑州市中心医院,450007

出　　处：《实用心电学杂志》2011年第1期30-32,共3页Journal of Practical Electrocardiology

摘　　要：目的探讨窦性心率震荡与2型糖尿病的关系。方法选择2型糖尿病患者46例和正常对照组50例,根据24h动态心电图记录分别计算其窦性心率震荡(HRT)的两个参数指标震荡初始(TO)和震荡斜率(TS)以及HRV中全部NN间期的标准差(SDNN)。结果①2型糖尿病组TO、TS、SDNN阳性检出率均高于正常组。②糖尿病合并慢性并发症组TO高于无慢性并发症组,糖尿病合并慢性并发症组TS低于无慢性并发症组(P<0.05)。结论 2型糖尿病患者HRT减弱或消失、HRV减弱,提示HRT及HRV可以作为动态评价2型糖尿病患者自主神经功能紊乱的一个可靠无创指标。Objective To observe the relation of the sinus heart rate turbulence （HRT） and type 2 diabetes. Methods 24h dynamic electrocardiograms were recorded in 46 patients with type 2 diabetes and 50 healthy persons （control group） then the SDNN and the HRT of each group of turbulence onset （ TO ） and turbulence slope （ TS ） were measured and the relation of these indexes was analyzed. Results ①The positive detection rate of the TO, TS, SDNN of patients with type 2 diabetes were higher than the control group. ②Higher TO was found in type 2 diabetes patients with chronic complications than those without chronic complications; On the contrary,lower TS in type 2 diabetes patients with chronic complications than those without chronic compllcations（ P 〈 0.05）. Conclusion HPR was abated or disappeared in patients with type 2 diabetes , and HRV was abated, which implied HRT and HRV may be used as a reliable and noninvasive indexes to evaluating the autonomic dysfunction in type 2 diabetes patients .

关 键 词：2型糖尿病 窦性心率震荡 心率变异性 

分 类 号：R540.41[医药卫生—心血管疾病]