无创正压通气治疗COPD并发Ⅱ型呼吸衰竭40例疗效观察  

Clinical Efficacy of Noninvasive Positive Pressure Ventilation on 40 Cases with Chronic Obstructive Pulmonary complicated with Type Ⅱ Respiratory Failure

作　　者：刘超峰[1] 

机构地区：[1]郑州煤炭工业集团有限责任公司总医院,河南郑州452371

出　　处：《中国医药指南》2012年第4期45-46,共2页Guide of China Medicine

摘　　要：目的探讨无创正压通气治疗COPD并发Ⅱ型呼吸衰竭的临床疗效。方法选择慢性阻塞性肺病合并Ⅱ型呼吸衰竭患者80例,随机分为观察组和对照组。两组均给予常规治疗,对照组给予持续低流量吸氧,观察给予无创正压通气。观察两组患者治疗前和治疗后动脉血气情况。结果观察组治疗后pH值显著高于对照组治疗后,差异有统计学意义(P<0.05);观察组治疗后PaO2显著高于对照组治疗后,差异有统计学意义(P<0.05);观察组治疗后PaCO2显著低于对照组治疗后,差异有统计学意义(P<0.05);观察组治疗后呼吸频率和心率显著低于对照组,差异有统计学意义(P<0.05)。结论无创正压通气治疗能够显著改善慢性阻塞性肺病并发Ⅱ型呼吸衰竭患者临床症状和体征,改善血气指标,临床效果显著。Objective To explore the clinical efficacy of noninvasive positive pressure ventilation on chronic obstructive pulmonary complicated with type II respiratory failure. Methods 80 cases with chronic obstructive pulmonary complicated with type II respiratory failure were selected,and divided into observation group and control group. The routine treatment was use to two groups,persistent low flow oxygen inspiration was given to control group. noninvasive positive pressure ventilation was used to observation group, blood gas analysis was detected before and after treatment. Results The value of pH in observation group after treatment compared with that in control group,there was statistical difference（P〈 0.05）; PaO2 in observation group after treatment is higher than that in control group,there was statistical difference（P〈0.05）; PaCO2 in observation group after treatment is lower than that in control group,there was statistical difference（P〈0.05）;the heart rate and respiratory rate in observation group after treatment is lower than that in control group,there was statistical difference（P〈 0.05）. Conelusions Noninvasive positive pressureventilation can improve the clinical symptoms and signs of chronic obstructive pulmonary complicated with type II respiratory failure,and improve blood gas indexes,the clinical efficacy is significant.

关 键 词：慢性阻塞性肺病 呼吸衰竭 无创正压通气 

分 类 号：R563.8[医药卫生—呼吸系统]