儿童单纯性肥胖危险因素分析及与血浆D-二聚体的相关性  

Analysis of risk factors of childhood simple obesity and its relationship with plasma D-dimer

作　　者：张晓杰[1] 刘静[1] 孙利伟[1] 田玉玲[1] 

机构地区：[1]长春市儿童医院,吉林长春130051

出　　处：《临床儿科杂志》2012年第2期157-159,共3页Journal of Clinical Pediatrics

摘　　要：目的探讨儿童单纯性肥胖的危险因素以及血浆D-二聚体与肥胖的相关性。方法采用问卷调查和体格测量的方法调查2006年1月—2010年12月就诊的单纯性肥胖儿童530例,其中102例测定血浆D-二聚体。同时选取120例性别、年龄、地区分布相匹配的健康儿童作对照,其中89例测定血浆D-二聚体。结果肥胖儿童出生体质量、其父母平均体质指数(BMI)均较对照组明显增高,差异有统计学意义(P均<0.01);肥胖儿童较正常对照儿童每日运动时间少,睡眠时间和看电视时间多,差异均有统计学意义(P均<0.01);儿童肥胖与饮食有关;肥胖儿童有心血管病家族史的比例明显高于对照组,血浆D-二聚体含量[(0.85±0.31)mg/L]亦较对照组[(0.30±0.11)mg/L]明显增高,差异均有统计学意义(P<0.001)。结论儿童肥胖是遗传因素和环境因素共同作用的结果,血浆D-二聚体与儿童单纯性肥胖具有相关性。Objective To investigate the risk factors of children simple obesity and the association of plasma D-dimer and children simple obesity.Methods The height and body weight of 530 outpatients with simple obesity were measured and questionnaire survey was processed from January 2006 to December 2010.The plasma D-dimer was tested in 102 children of them.Meanwhile,120 healthy children were selected as control with matched gender,age and region.The plasma D-dimer was also measured.Results The birth weight and the mean parents BMI of obese children were significantly higher than those of control group(P < 0.01).Compared with the control group,obese children daily exercised less time but spent more time on sleeping and watching TV(all P < 0.01).Children obesity was diet related,and the percentage of family history of cardiovascular disease and the levels of D-dimer in obese children were significantly higher than those in control group(P < 0.001).Conclusions Obesity in children is determined by genetic and environmental factors.The plasma D-dimer is related to children simple obesity.

关 键 词：肥胖 危险因素 血浆D二聚体 儿童 

分 类 号：R723[医药卫生—儿科]