非超重患者心周脂肪含量与冠心病及代谢危险因素的关系  

The association of pericardial adipose tissue with coronary artery disease and metabolic risk factors in non-overweight patients

作　　者：费军[1] 贾付坤[2] 刘瑛琪[2] 刘军华[1] 陈宁[1] 郑冬[1] 张朝利[1] 

机构地区：[1]解放军306医院放射科,北京100101 [2]解放军306医院心内科,北京100101

出　　处：《放射学实践》2012年第2期164-166,共3页Radiologic Practice

摘　　要：目的:探讨非超重患者心周脂肪(PAT)含量与冠心病及代谢危险因素之间的关系。方法:选取因胸痛行冠状动脉CTA检查的非超重患者(BMI<24kg/m2)418例,测定PAT含量、冠脉钙化积分,根据冠状动脉直径狭窄≥50%将患者分为冠心病组和非冠心病组;根据血管受累数目及代谢危险因素的数量将患者分组,比较各组间PAT含量。结果:冠心病组[(195.30±77.04)cm3]较非冠心病组[(165.03±56.66)cm3]PAT含量明显增加(P<0.001)。随血管受累支数及代谢危险因素数目的增加,PAT含量呈上升趋势,组间差异有显著性意义(P<0.05)。结论:MSCT测定PAT含量是提示非超重患者冠心病和代谢风险的方法之一。Objective：To explore the relationship between volume of PAT and coronary artery atherosclerosis in non-overweight patients.Methods：A total of 418 patients with body mass index（BMI） under 24kg/m2 were studied.Cardiac multislice computed tomography was used to measure PAT volume,coronary artery calcium score and Gensini score.The patients were divided into coronary artery disease（CAD） and non-CAD group based on the presence of ≥50% stenosis.The patients were grouped according to the number of vessels involved and the number of metabolic risk factors,then PAT volume was compared among the groups.Results：PAT volume was significantly higher in patients with CAD than that in non-CAD subjects [（195.30±77.04）cm3 vs（165.03±56.66）cm3,P0.0001].As the number of vessels involved and the number of metabolic risk factors increased,the volume of PAT increased correspondingly.There was a significant difference among the groups（P0.05）.Multiple logistic regression analysis showed that PAT volume was significantly associated with BMI and waist circumference.Conclusion：MDCT measurement of pericardial adipose tissue volume can be applied as one of the indicators of coronary artery disease and metabolic risk in non-overweight patients.

关 键 词：心周脂肪 冠状动脉硬化 体层摄影术 X线计算机 

分 类 号：R541.4[医药卫生—心血管疾病]