缺氧诱导脑红蛋白表达及运动生物学应用展望  

Neuroglobin expression induced by hypoxia and expectation for its application in sports biology

作　　者：邢维新 田振军[2] 

机构地区：[1]丽江师范高等专科学校体育系,云南丽江674100 [2]陕西师范大学体育学院,陕西西安710062

出　　处：《体育学刊》2012年第1期139-144,共6页Journal of Physical Education

基　　金：国家自然科学基金项目(31040045);陕西师范大学"211工程"重点建设学科--运动生物学重点学科建设项目资助

摘　　要：脑红蛋白(Ngb)是新近发现的神经系统特异的携氧球蛋白,主要在脊椎动物脑组织中高表达,与脑内氧供应密切相关。研究表明,缺氧能够诱导Ngb的表达,而高表达的Ngb能够保护神经元免受缺氧损伤,从而在神经系统缺氧、缺血损伤中具有重要的神经保护功能。从Ngb的生物学特征研究出发,对Ngb在医学中的研究现状做一综述,并对Ngb在体育科学中的应用前景进行展望。Neuroglobin（Ngb） is a newly discovered particular oxygen carrying globin in the nervous system,mainly expressed in the brain tissues of vertebrates at a high level,closely related to oxygen supply in brains.It is indicated in researches that hypoxia can induce the expression of Ngb,while Ngb expressed at a high level can pro-tect neurons from being damaged by hypoxia,thus it is provided with an important nerve protecting function in nervous system damages caused by hypoxia or ischemia.By studying the biological characteristics of Ngb,the au-thors gave an overview of the current situation of Ngb study in medical science,and expected the application of Ngb in sports science.

关 键 词：运动生物化学 脑红蛋白 运动 缺氧 综述 

分 类 号：G804.7[文化科学—运动人体科学]