拉米夫定治疗乙肝合并抗结核药致肝功损害的临床研究  

Clinical study on Lamivudine in treatment of hepatitis B combined with antituberculosis-induced hepatic lesion

作　　者：端木和运[1] 曹惠娟[1] 

机构地区：[1]常州市第三人民医院肺科,江苏常州213001

出　　处：《临床肺科杂志》2012年第3期479-480,共2页Journal of Clinical Pulmonary Medicine

摘　　要：目的探讨拉米夫定在HBVDNA阳性合并肺结核患者的治疗作用。方法选择抗结核治疗及中药保肝后,肝功能再次异常30例,且HBVDNA阳性30例,予拉米夫定抗病毒治疗并中药保肝治疗,肝功能恢复正常后,恢复抗结核治疗,完成疗程。结论 HBVM且HBVDNA阳性,抗病毒治疗可以有效保护并恢复正常肝功能。Objective To investigate role of lamivudine in HBVDNA-positive cases with tuberculosis. Methods 30 cases with HBVDNA-positive whose liver function were damaged once again after giving anti-tubercluosis treatment were selected. Their liver function were recovered due to lamivudine antiviral treatment and hepatoprotection by traditional Chinese medicine. And then resumed anti-tubercular treatment, and completed the course. Conclusion antiviral treatment can effectively protect and restore normal liver function in HB- VDNA-positive cases with tuberculosis.

关 键 词：肺结核 HBVDNA 肝功能 抗病毒 

分 类 号：R512.62[医药卫生—内科学]